Consortium finds immune related MicroRNA changes in MS
Posted: Thu Aug 12, 2010 10:51 pm
A pair of microRNAs thought to regulate immune genes are found at lower levels in the blood of those with multiple sclerosis than in unaffected individuals, according to a study appearing online yesterday in PLoS ONE.
Members of the Australia and New Zealand Multiple Sclerosis Genetics Consortium, known as ANZgene, used miRNA microarray profiling to compare miRNA patterns in blood samples from 59 individuals with MS and 37 unaffected controls. The researchers found lower expression of two miRNAs — miR-17 and miR-20a — in individuals with all three forms of MS tested in the study.... Read More - http://www.msrc.co.uk/index.cfm/fuseact ... ageid/1863