The genetic basis of multiple sclerosis:a model for MS
Posted: Fri Oct 29, 2010 3:17 am
MS-pathogenesis is known to involve both multiple environmental events, and several independent genetic risk-factors.
Methods: A model of susceptibility is developed and a mathematical analysis undertaken to elucidate the nature of genetic susceptibility to MS and to understand the constraints that are placed on the genetic basis of MS, both by the known epidemiological facts of this disease and by the known frequency of the HLA DRB1*1501 allele in the general populations of northern Europe and North America. ... Read More - http://www.msrc.co.uk/index.cfm/fuseact ... ageid/1347