Hypogelsolinemia, in MS patients
Posted: Mon Nov 01, 2010 11:46 pm
Hypogelsolinemia, a disorder of the extracellular actin scavenger system, in patients with MS.
Extracellular gelsolin (GSN) and GC-globulin /Vitamin D-binding protein (DBP) appear to play an important role in clearing the actin from extracellular fluids and in modulating cellular responses to anionic bioactive lipids.
In this study we hypothesized that cellular actin release and/or increase in bioactive lipids associated with multiple sclerosis (MS) development will translate into alteration of the actin scavenger system protein concentrations in blood and cerebrospinal fluid (CSF) of patients with MS....Read More - http://www.msrc.co.uk/index.cfm/fuseact ... ageid/1461
Extracellular gelsolin (GSN) and GC-globulin /Vitamin D-binding protein (DBP) appear to play an important role in clearing the actin from extracellular fluids and in modulating cellular responses to anionic bioactive lipids.
In this study we hypothesized that cellular actin release and/or increase in bioactive lipids associated with multiple sclerosis (MS) development will translate into alteration of the actin scavenger system protein concentrations in blood and cerebrospinal fluid (CSF) of patients with MS....Read More - http://www.msrc.co.uk/index.cfm/fuseact ... ageid/1461