Re: A new concept and treatment options for MS
Posted: Wed Aug 06, 2014 1:35 am
I tend to see the Herpes virus is a constellation or a cluster of viruses, all of the same HERV family.
I think if you have a high load of EBV immune complexes, you are also likely to have a high load of other immune complexes such as Herpes simplex and Varicella Zoster. In my case, both EBV and Herpes simplex were about 20 times max. Varicella Zoster was not tested but I am sure that reading will be high as well. I remember red spots in the neck when shaving, before the MS diagnosis; this is a sign of Varicella Zoster.
The virus is with us for many millions of years, I tend to think the immune system is playing a cat and mouse game with the virus where its appearance may change over time. Where Herpes simplex is more inflammatory (in RR phase), Varicella Zoster may cause more permanent vasculopathy from microbleedings http://download.springer.com/static/pdf ... 9&ext=.pdf http://www.sciencedirect.com/science/ar ... 0X14000689 and EBV is earmarked as an onco virus. So the virus (or should I say viruses) work on different fronts using different mechanisms (as seen from within our current medical concepts).
Raltegravir is probably more effective than (val)acyclovir as the posting below suggests. I think that the case of the woman described here is not a-typical at all. http://omicsonline.org/evidence-that-ra ... ?aid=18477
I wonder whether we could or should combine the raltegravir therapy with rituximab (rituxan) http://en.wikipedia.org/wiki/Rituximab for a while (say few months) to keep the B-cells down and/or; with neuro muscular electric stimulation (see the above publication on Varicella Zoster which suggests "A newer potentially promising treatment for PHN is percutaneous peripheral nerve field stimulation" - remember Terry Wahls' success with NMES which was probably as important as her diet).
One possibility to get going quickly would be to sign a written consent for off-label use of Raltegravir at a standard dose of 400 mg twice a day. Any one any ideas?
I think if you have a high load of EBV immune complexes, you are also likely to have a high load of other immune complexes such as Herpes simplex and Varicella Zoster. In my case, both EBV and Herpes simplex were about 20 times max. Varicella Zoster was not tested but I am sure that reading will be high as well. I remember red spots in the neck when shaving, before the MS diagnosis; this is a sign of Varicella Zoster.
The virus is with us for many millions of years, I tend to think the immune system is playing a cat and mouse game with the virus where its appearance may change over time. Where Herpes simplex is more inflammatory (in RR phase), Varicella Zoster may cause more permanent vasculopathy from microbleedings http://download.springer.com/static/pdf ... 9&ext=.pdf http://www.sciencedirect.com/science/ar ... 0X14000689 and EBV is earmarked as an onco virus. So the virus (or should I say viruses) work on different fronts using different mechanisms (as seen from within our current medical concepts).
Raltegravir is probably more effective than (val)acyclovir as the posting below suggests. I think that the case of the woman described here is not a-typical at all. http://omicsonline.org/evidence-that-ra ... ?aid=18477
I wonder whether we could or should combine the raltegravir therapy with rituximab (rituxan) http://en.wikipedia.org/wiki/Rituximab for a while (say few months) to keep the B-cells down and/or; with neuro muscular electric stimulation (see the above publication on Varicella Zoster which suggests "A newer potentially promising treatment for PHN is percutaneous peripheral nerve field stimulation" - remember Terry Wahls' success with NMES which was probably as important as her diet).
One possibility to get going quickly would be to sign a written consent for off-label use of Raltegravir at a standard dose of 400 mg twice a day. Any one any ideas?