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Scientists probe strategies to repair neuron damage in MS

Posted: Wed Mar 02, 2011 12:29 am
by MSUK
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Scientists working collaboratively around the world say they are coming closer to developing therapies that may help restore neurologic function in patients with multiple sclerosis (MS). However, they caution that such therapies are only beginning to enter early clinical trials and may be years from the clinic.

Most existing therapies for MS aim to tamp down aberrant immune function and are especially helpful for some phases of the disease, although patients may still progress to a chronic, more progressive stage of illness. In addition, some newer therapies aim to reduce specific symptoms of the disorder. For example, the US Food and Drug Administration recently approved dextromethorphan hydrobromide and quinidine sulfate to treat pseudobulbar affect, a condition marked by uncontrolled emotional outbursts that may develop in patients with MS or certain other neurologic disorders....Read More - http://www.msrc.co.uk/index.cfm/fuseact ... ageid/1845

Posted: Wed Mar 02, 2011 2:07 am
by Algis
However, they caution that such therapies are only beginning to enter early clinical trials and may be years from the clinic.
Means "decades" right? :P

Posted: Wed Mar 02, 2011 7:49 am
by dignan
It's not that bad Algis. A drug can get through the clinical trial process in less than 10 years. It really depends on how much money the sponsors have and how organized they are. Phase 3 trials are typically 2 years. Phase 2 trials are typically around 1 year and phase 1 trials are around 1-3 months. So that is only about 3.25 years in total trial time to get approval. The problem is how much time it takes to recruit participants and set up the trials. But it doesn't add up to decades, maybe a single decade, maybe less.

Posted: Wed Mar 02, 2011 9:33 pm
by Algis
Might the Gods (and their Brothers) listen to you dignan :)