MRI correlates of cognitive impairment in childhood-onset MS
Posted: Fri May 06, 2011 3:47 am
Abstract
Objective: Brain MRI measures were correlated with neuropsychological function in 35 pediatric-onset multiple sclerosis (MS) patients and 33 age- and sex-matched healthy controls.
Method: Mean age of MS patients was 16.3 ± 2.3 years with average disease duration of 4.3 ± 3.1 years. Cortical gray matter, thalamic, and global brain volumes were calculated for all participants using a scaling factor computed using normalization of atrophy method to normalize total and regional brain volumes for head size. T1- and T2-weighted lesion volumes were calculated for MS patients....Read More - http://www.msrc.co.uk/index.cfm/fuseact ... ageid/1408