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molecule to block EBV

Posted: Wed Aug 31, 2011 9:33 pm
by rainer
Sort of think a EBV forum might be useful.

http://www.prohealth.com/library/showar ... ibid=16467 (this is a commercial supplement site - fyi)

http://www.ncbi.nlm.nih.gov/pubmed/21673108

Using molecular mapping of an immune memory cell ‘bio-antenna’ that EBV hijacks for its own ends, a Danish team has identified a tiny molecule that can foil the process and may be manipulated to block EBV’s role in immune system cancers.

The Epstein-Barr herpes virus (HHV-4) causes mononucleosis but is also associated with immune system cancers and autoimmune diseases. Infection with EBV means that the B cells, which are the primary memory cells of the immune system, are being hijacked.

Now researchers at the University of Copenhagen report they’ve found a way to regulate a special receptor or “bio-antenna” that plays a vital part when EBV infects us - and when this infection appears to be mutating into cancer of the immune system. (Their report was published online Aug 19 by The Journal of Biological Chemistry.)

Posted: Wed Aug 31, 2011 11:19 pm
by Scott1
Hi Rainer,

I agree. I found the following links which I think are interesting.

http://machineslikeus.com/news/do-you-need-your-tonsils

This one talks about the role of CD56bright cells which are a natural killer cell produced in the tonsils. They should help to control EBV.

This one-

http://www.ncbi.nlm.nih.gov/pubmed/19758707

refers to the boost to CD56 Bright cell production from using Interferon Beta 1a.

I have been thumping the table about using the combination of 1)Valtrex for which there is a lot of evidence that it disrupts the replication of EBV and 2)Avonex. These links show how Interferon Beta 1a boosts the front line defences in the tonsils where the research I posted implies our problems start.
I'm still convinced you need both and you need very long term use of both to gain a sustained benefit.
I'm having my EBV levels checked at the moment as well as my 25 dihydroxyvitamin d levels measured. Hopefully after years of doing what I have been describing the EBV is low. I expect my uric acid will be high because the Valtrex is a purine. I've no idea what the vitamin d will look like but if its outside normal I won't be surprised.
Regards