Breakthrough in the development of possible therapy for MS
Posted: Wed Oct 19, 2011 7:47 am
Multiple sclerosis and psoriasis are two of the most common autoimmune diseases. Most surprisingly, almost any therapy effective in one of the two diseases causes rather harm in the other, even though similar modes of inflammation underlie both diseases.
A research group of the Tübingen University Hospital studied a small, body-derived molecule called di-methyl fumarate (DMF), that is the first molecule improving both diseases psoriasis and multiple sclerosis. They found that this body-derived molecule strongly influences natures most potent immune stimulators, the dendritic cells that have recently been awarded by the Nobel Prize to Ralph Steinman.
Normally, dendritic cells should recognise danger caused by bacteria or viruses, alarm the immune system and raise protective responses.
Unfortunately, when fooled, dendritic cells induce by error immunity against the bodys own cells and start to destroy them.... Read More - http://www.msrc.co.uk/index.cfm/fuseact ... ageid/1894