Is your ANA positive? Do you have neuropathy? GERD?
Posted: Thu Nov 10, 2011 3:39 pm
Hello!
I've been having some symptoms for the last 18 months and pretty serious ones for the last year, and I still don't have a diagnosis. My family doctor was certain I had MS when my symptoms first started up so I read a lot about the disease and resigned myself to the fact that I had it... then my MRI came back clear. The neurologist I saw felt that the likelihood I had MS was very small, but had no idea what I did have so he ran a lot of bloodwork. It's clear that I do have an autoimmune disease of some sort because my ANA was a high positive (1:640 speckled) and my rheumatoid factor was initially positive though I've had a retest since then and it was negative. Rheumatoid factor can be positive in RA of course, but also several other diseases.
I was referred to a rheumatologist and he felt certain I had a connective tissue disease, but said time would tell which one it actually was. Based on my evolving symptoms he tended to think it was scleroderma, but could not yet make the diagnosis. So then I researched a ton about scleroderma and resigned myself to the fact that I had a disease that was likely fatal. My rheumatologist retired in June and I was sent to a new one who is not at all sure that I even have a connective tissue disease at all. She's inclined to think that it *is* MS after all! Needless to say, I'm frustrated and my emotions are all over the place. I have symptoms on a daily basis that range from mild to disabling. From the pattern of my symptoms, I tend to think that it's *not* MS, but I thought I'd ask you experts!
Here are my abnormal blood results:
low ferritin (iron stores) but normal hemoglobin
high white blood cell count (chronic, usually around 13)
pre-diabetic level blood glucose levels (A1C of 6.0, fasting BG 5.9, post-meal readings up to 12.0)
high levels of chromium in blood
low vitamin D
ANA + (1:640 speckled)
positive rheumatoid factor
My MRI of brain and spine was clear (no lesions). My EEG was normal, as was the NCV/EMG. I also had a normal echocardiogram (mild mitral valve prolapse noted) and EKG.
I have PCOS (polycystic ovaries) and have had half my thyroid removed though the function of the remaining portion is still good. I'm 30 years old, a healthy weight, eat fairly well, and am moderately active.
My symptoms are: polyneuropathy (mostly tingling but sometimes burning/itching/pricking/wet sensations, worst in feet and legs, but occurs in my hands, a spot on my back, my pelvic area, over my scalp, tongue, lips, and one side of my face - the left - as well sometimes), suspected autonomic neuropathy (episodes of 3-4 hours at a time where I get extremely cold and shivery, constantly have to use the bathroom, get dizzy, blurry vision, and have trouble thinking clearly along with tingling over most of my body), atypical migraines, mild joint/muscle pain, mild muscle weakness, heart palpitations, sensations of the skin on my face and arms/hands tightening and stiffening, circulation problems (extremities are always ice cold in cooler weather, blueish/grey and splotchy, with numbness and tingling), and GERD.
I am on medications for GERD and my circulation (a calcium channel blocker), but nothing else.
I would love to hear feedback on whether any of this is in line with your own symptoms. Do you have a positive ANA? Low vitamin D?
All the best,
Zoe
I've been having some symptoms for the last 18 months and pretty serious ones for the last year, and I still don't have a diagnosis. My family doctor was certain I had MS when my symptoms first started up so I read a lot about the disease and resigned myself to the fact that I had it... then my MRI came back clear. The neurologist I saw felt that the likelihood I had MS was very small, but had no idea what I did have so he ran a lot of bloodwork. It's clear that I do have an autoimmune disease of some sort because my ANA was a high positive (1:640 speckled) and my rheumatoid factor was initially positive though I've had a retest since then and it was negative. Rheumatoid factor can be positive in RA of course, but also several other diseases.
I was referred to a rheumatologist and he felt certain I had a connective tissue disease, but said time would tell which one it actually was. Based on my evolving symptoms he tended to think it was scleroderma, but could not yet make the diagnosis. So then I researched a ton about scleroderma and resigned myself to the fact that I had a disease that was likely fatal. My rheumatologist retired in June and I was sent to a new one who is not at all sure that I even have a connective tissue disease at all. She's inclined to think that it *is* MS after all! Needless to say, I'm frustrated and my emotions are all over the place. I have symptoms on a daily basis that range from mild to disabling. From the pattern of my symptoms, I tend to think that it's *not* MS, but I thought I'd ask you experts!
Here are my abnormal blood results:
low ferritin (iron stores) but normal hemoglobin
high white blood cell count (chronic, usually around 13)
pre-diabetic level blood glucose levels (A1C of 6.0, fasting BG 5.9, post-meal readings up to 12.0)
high levels of chromium in blood
low vitamin D
ANA + (1:640 speckled)
positive rheumatoid factor
My MRI of brain and spine was clear (no lesions). My EEG was normal, as was the NCV/EMG. I also had a normal echocardiogram (mild mitral valve prolapse noted) and EKG.
I have PCOS (polycystic ovaries) and have had half my thyroid removed though the function of the remaining portion is still good. I'm 30 years old, a healthy weight, eat fairly well, and am moderately active.
My symptoms are: polyneuropathy (mostly tingling but sometimes burning/itching/pricking/wet sensations, worst in feet and legs, but occurs in my hands, a spot on my back, my pelvic area, over my scalp, tongue, lips, and one side of my face - the left - as well sometimes), suspected autonomic neuropathy (episodes of 3-4 hours at a time where I get extremely cold and shivery, constantly have to use the bathroom, get dizzy, blurry vision, and have trouble thinking clearly along with tingling over most of my body), atypical migraines, mild joint/muscle pain, mild muscle weakness, heart palpitations, sensations of the skin on my face and arms/hands tightening and stiffening, circulation problems (extremities are always ice cold in cooler weather, blueish/grey and splotchy, with numbness and tingling), and GERD.
I am on medications for GERD and my circulation (a calcium channel blocker), but nothing else.
I would love to hear feedback on whether any of this is in line with your own symptoms. Do you have a positive ANA? Low vitamin D?
All the best,
Zoe