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Therapeutic potential of carbon monoxide in MS

Posted: Thu Jan 19, 2012 1:10 am
by MSUK
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Abstract
Carbon monoxide (CO) is produced during the catabolism of free haem, catalyzed by haem oxygenase (HO) enzymes, and its physiological roles include vasodilation, neurotransmission, inhibition of platelet aggregation and anti-proliferative effects on smooth muscle.

In vivo preclinical studies have shown that exogenously administered quantities of CO may represent an effective treatment for conditions characterized by a dysregulated immune response....Read More - http://www.msrc.co.uk/index.cfm/fuseact ... ageid/1327