7T MRI depicts Multiple Sclerosis lesions
Posted: Tue Feb 21, 2012 6:02 am
Ultrahigh-field strength, T1-weighted magnetization-prepared rapid acquisition and multiple gradient echoes (MPRAGE) is highly sensitive for detecting multiple sclerosis (MS) plaques within the white and gray brain parenchyma, according to a study published online Feb. 20 in Archives of Neurology, one of the JAMA/Archives journals.
In current clinical practice, T2-weighted MRI is commonly used to quantify the accumulated MS lesion load in the brain, whereas T1-weighted sequences are used to differentiate irreversible brain tissue damage, hyperintense lesions commonly called “black holes.” Black holes are associated with clinical worsening and cerebral atrophy. On spin-echo T1-weighted images, a proportion of T2 hyperintense lesions appears hypointense to the surrounding normal-appearing white matter for a long time, the researchers noted.... Read More - http://www.msrc.co.uk/index.cfm/fuseact ... ageid/1816