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herpes virus in monkeys that causes an MS like disease

Posted: Fri Mar 02, 2012 1:43 pm
by Liberation
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Re: herpes virus in monkeys that causes an MS like disease

Posted: Sun Mar 04, 2012 2:05 pm
by JSpeece
I was at OHSU the other day and had my blood drawn for this study. When they have the results I will receive an email and will provide a link. Obviously it will be awhile before that happens.

On a humorous side note. My friends had a field day with me when I told them I was getting tested for "Monkey Herpes".

Re: herpes virus in monkeys that causes an MS like disease

Posted: Sun Mar 04, 2012 2:59 pm
by civickiller
EBV possibly too

Re: herpes virus in monkeys that causes an MS like disease

Posted: Wed Mar 07, 2012 12:55 pm
by Interrupted
Herpes groups? They're continuing on the right track at last.

Re: herpes virus in monkeys that causes an MS like disease

Posted: Wed Mar 14, 2012 1:36 am
by Leonard
correct, see also last page http://www.thisisms.com/forum/general-d ... 8-285.html that explain the role of virus blocking receptors

Re: herpes virus in monkeys that causes an MS like disease

Posted: Fri Feb 19, 2016 12:08 pm
by leonardo
Immunopathology of Japanese macaque encephalomyelitis is similar to multiple sclerosis.
Japanese macaque encephalomyelitis (JME) is an inflammatory demyelinating disease that occurs spontaneously in a colony of Japanese macaques (JM) at the Oregon National Primate Research Center. Animals with JME display clinical signs resembling multiple sclerosis (MS), and magnetic resonance imaging reveals multiple T2-weighted hyperintensities and gadolinium-enhancing lesions in the central nervous system (CNS). Here we undertook studies to determine if JME possesses features of an immune-mediated disease in the CNS. Comparable to MS, the CNS of animals with JME contain active lesions positive for IL-17, CD4+ T cells with Th1 and Th17 phenotypes, CD8+ T cells, and positive CSF findings.
http://www.ncbi.nlm.nih.gov/pubmed/26857488

Re: herpes virus in monkeys that causes an MS like disease

Posted: Fri Feb 19, 2016 3:05 pm
by euphoniaa
FYI to those who noticed that this thread was bumped from 2012, the PubMed report that leonardo linked to today is current and dated Feb. 15, 2016. :smile:

Re: herpes virus in monkeys that causes an MS like disease

Posted: Fri Feb 19, 2016 6:20 pm
by 1eye
This shows 2 things: how close macaque genetics and physiology is to human, and in fact, that what they may have is actual MS, for all intents and purposes. Rather than go into the macaque euthanasia business, if you cure the macaque disease, haven't you also cured the human one?

Why doesn't somebody try using all these MS drugs that are supposed to be disease-modifying, on the sick macaques? There's certainly a lot of veterinary-grade biotin around. They might benefit from a CCSVI procedure. Somebody should be checking to see if they have something similar. If so, what might be the prevalence?

Re: herpes virus in monkeys that causes an MS like disease

Posted: Sat Feb 20, 2016 6:45 pm
by CureOrBust
I did a search for this latest paper, and came across the following. The first link includes (starts on about page 9) what may be the full original article (was from 2011 and from the same institute) http://www.dtic.mil/dtic/tr/fulltext/u2/a553928.pdf

Re: herpes virus in monkeys that causes an MS like disease

Posted: Sun Feb 21, 2016 9:36 am
by Leonard
Liberation wrote:"Now Japanese Macaques could hold the key to helping people like Susan. Scientists at the Oregon National Primate Center have discovered a new herpes virus in monkeys that causes an MS like disease in Macaques.

These brain lesions are a classic indicator of inflammation in people with MS. The discovery could help scientists solve how the disease develops and stop its onset. "

http://www.stemcelldoctors.org/multiple ... ith-ms.php

of course, MS is cause by the herpes virus, in casu VZV and EBV.
see also the thesis on http://www.thisisms.com/forum/general-d ... 27300.html

Re: herpes virus in monkeys that causes an MS like disease

Posted: Sun Feb 21, 2016 2:06 pm
by 1eye
No MS patient should let this pass without comment. What have we all been complaining about for the last 30 or so years? The horrors, MS sucks, chronic problems, etc. So it's somehow OK to give it to another animal, as long as they aren't human? Well, I wouldn't claim to be human if I didn't already have that unfortunate diagnosis.

Oh, boy. Give the Japanese macaques MS, probably put them through ten years of testing, then kill them. Fun with science. Survival of the individual proves nothing. An individual, fit or not, will contribute eagerly to the extinction of any or all species, especially their own, if there is money in it.

May have to recuse myself from any further use of MS drugs. :-( My heart would be broken anyway...