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squiffy2 wrote:Stanford University grants rights for exclusive use of Lisinopril in Multiple Sclerosis



Transparency Life Sciences, LLC (TLS) the world's first drug development company based on open innovation and crowdsourcing, today announced that it has concluded an agreement with Stanford University giving the company an exclusive option to license intellectual property covering the use of lisinopril as a treatment for multiple sclerosis (MS).

Separately, TLS announced that MS expert Dr. Lawrence Steinman, the George A. Zimmermann Professor of Neurology and Neurological Sciences & Pediatrics at the Stanford School of Medicine and Chair of the TLS Scientific Advisory Board, presented preclinical data on the potential of lisinopril in MS at a recent Gordon Conference.... Read More - http://www.msrc.co.uk/index.cfm/fuseact ... ageid/1397

euphoniaa wrote: I do feel obligated to point out a couple of things I've posted elsewhere also.

1. When they list a "dry cough" in the side effect profile, that's a major understatement. I found it more stressful and disabling than most anything MS has thrown at me. I disrupted many a meeting and lecture at work with my sudden coughing fits (sputter, gag, gasp, cough till you puke) and a good night's sleep was impossible. I assumed I had contracted some horrible bronchial illness that extended through a whole winter until someone mentioned The Lisinopril Cough (not my doc - she just added cough & sinus meds). Instead I dropped lisinopril and I was miraculously cured! You can Google the "ACE cough" or the "lisinopril cough" and find out more about it.

2. And before everyone runs out to ask for the "... inexpensive, safe pharmaceuticals used by millions worldwide..." they might want to consider the possibility that it may be contraindicated in your particular medical case and screwing around with your BP may be dangerous for you.

Although the treatment of high blood pressure has generally been a hit/miss/tryanotherdrug/miss/tryanotherdrug thing in the past (kinda like treating MS), now there's a machine that can tell them quickly where your problem lies and choose the best med for it - the Bio-Z machine. For example, it told them that the beta blocker I'd been taking was doing its job in that area and that my fluids were fine and I don't need to add a diuretic. It also said that I DO need to add something like an ACE inhibitor, but the side effects have prevented me from taking one.