Oral steroids effective in Multiple Sclerosis
Posted: Wed Apr 25, 2012 1:05 am
Outcomes for multiple sclerosis patients in relapse who were treated with oral methylprednisolone were no different than those of similar patients who received intravenous steroids, researchers reported here.
After 28 weeks, 16 of 22 patients (72.7%) given oral medication achieved at least a one point improvement in the standard Expanded Disability Status Scale compared with 16 of 23 patients (69.6%) who were treated with the drug IV (P=1.0), according to Cristina Ramo-Tello, MD, a staff neurologist at H. Germans Trias I Pujol Hospital in Badalona, Spain.
"We were able to show that 1,250 mg of oral methylprednisolone given daily for 3 days was not inferior to the bioequivalent 1,000 mg of methylprednisolone daily for 3 days administered intravenously," Ramo-Tello told MedPage Today at a poster presentation at the American Academy of Neurology meeting.... Read More - http://www.msrc.co.uk/index.cfm/fuseact ... pageid/776