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Decisions to change multiple sclerosis treatments soon after starting them appear to be driven more by MRI findings of increasing disease activity than worsened clinical symptoms, a researcher said here.

In a retrospective analysis of 606 patients showing suboptimal responses to an initial disease-modifying therapy, the factor showing the strongest association with a change in treatment was increased disease activity seen in MRI scans (odds ratio 6.3 compared with a single relapse alone, 95% CI 3.1-12.9), reported Barbara Teter, PhD, MPH, of the State University of New York at Buffalo....... Read More - http://www.ms-uk.org/index.cfm/technology

As they should. Here's an article that shows how advanced mri imaging can more closely connect the damage in the brain to clinical symptoms and why your current lack of symptoms doesn't mean that the lesions you have are simply in the 'silent' regions of your brain. Sorry to sound alarmist but better to know the implications so you can better make decisions abt direction of therapy.

This is best viewed on a computer vs smartphone so see the imagery and animation:
http://multiple-sclerosis-research.blog ... itive.html