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Each of us must determine what is right for us. My belief is the body will let you know
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Wrong, dead wrong! A blood test will tell you if you are in the right zone.
From what I have read toxic levels may occur at 50,000IU a day for extended periods
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I do realise that your medical knowledge is informed by your particular philosophy, but you really should read more widely. As little as 10,000iu can be bad for you - that's can not will - and you can read more here: http://www.mssociety.org.uk/forum/new-d ... rd-warning
The doctors ... ... will tell you to use tanning creams which cause cancer. That shows what they know.
Actually, it does tend to be indicative of whet you know. having travelled extensively from the Bay Area to Merced and down to San Diego, across to Southern Nevada, Western Arizona and Southern Utah, I do not recall a single person in the street wearing sunblock. Of course, it is possible that the MDs in that area of the US have not had the benefit of the word according to wanna, but I rather think not.
Geoff
Re: Vitamin D deficient....again!
Posted: Sat Jul 12, 2014 2:29 pm
by zjac020
As much as 10k IUs daily dangerous? Well im guessing a calcium tablet is dangerous for some.
Ive seen the MS societies take wayyyy to long to pay any interest to the vitamin D issue, just like big pharma, now isnt that a coincidence.
Vitamin D is not simply a vitamin, its more of a hormone and its fat soluble so the body does store it, thus it can be toxic that is why you need to alter your supplement depending on how much natural vitamin d providing sunlight your getting and what your blood serum level is. But 10k IUs daily is perfectly safe for 99.99999% of people, not to mention MS sufferers.
Re: Vitamin D deficient....again!
Posted: Sat Jul 12, 2014 10:03 pm
by THX1138
But 10k IUs daily is perfectly safe for 99.99999% of people, not to mention MS sufferers.
In addition to myself, that I am aware of, there is at least one other person at TiMS alone who had serious trouble from 10k daily or less.
This is likely caused from the neuromuscular hyperexcitability of magnesium deficiency that is somehow unmasked by higher Vitamin D levels.1
Anyone else here have "neuromuscular hyperexcitability"
I sure do and I know it is from too much D along with not enough Mg to counteract 1-2 years of 5k to 10k of vitamin/hormone D.
Too Much Vitamin D?
Carolyn Dean MD ND | Sunday, March 10, 2013
A client emailed that he heard a doctor on a talk show recommending 5,000 IU of Vitamin D instead of the RDA of 400 IU. He asked me what I thought.
I said that everyone thinks there’s a Vitamin D deficiency epidemic but I’m not convinced. The big question is, why all of a sudden are we so deficient. What could Vitamin D be responding to and what do the low levels indicate?
Here’s one possible answer. Vitamin D is really a hormone with a feedback loop to calcium. When the body has enough calcium less Vitamin D is required and the levels drop.
We are a calcified country, so the effect of high calcium may be lower levels of Vitamin D. And without understanding the complex chemistry involved, most people think we just need to take more.
But MORE Vitamin D pulls in more calcium and bumps out magnesium, making people more magnesium deficient.
Taking high dose Vitamin D (anything above 2,000 IU) will also use up your magnesium because this mineral is required to change the supplemental/storage form of Vitamin D into active Vitamin D.
Not everyone is going to suffer from too much Vitamin D and enough people seem to benefit from it (at least in the short term) that it’s not going to ring any alarm bells for many years. After all, it took about 3 decades for us to realize that high dose calcium supplementation was causing heart disease and soft tissue calcification when not properly balanced with magnesium.
I don't want to be disagreeable, but I sure don't want others to develop debilitating muscle problems and incorrectly attribute them to MS when the problems came on deceptively gradually as a result of taking too much vitamin/hormone D.
Re: Vitamin D deficient....again!
Posted: Sun Jul 13, 2014 3:21 am
by zjac020
in this case then it's not just vitamin d. in the same way one tries to optimize d levelsnyou need to optimize other key nutrients and minerals incl. ofcourse mag.
Re: Vitamin D deficient....again!
Posted: Sun Jul 13, 2014 4:55 am
by want2bike
I am a believer in the importance of vitamin D in fighting disease but I also realize these vitamins and minerals work together to give us good health. Magnesium is not a concern for me since I eat lots of leafy greens everyday. My magnesium levels are through the roof. Eating lots of raw fruits and vegetables should give us the vitamins and minerals we need except for the vitamin D which is the sunshine vitamin. It is best to get it from the sun but that is hard to do in the winter. Each of us must pay attention to our bodies and give it the nutrients it needs if we want to be healthy. Most of the information I have seen suggest vitamin D is important for people with MS. If you are having trouble with vitamin D might be best to address the magnesium issue.
Re: Vitamin D deficient....again!
Posted: Sun Jul 13, 2014 6:31 am
by zjac020
i on the other hand cant really get my magnesium into the higher levels despite consuming lots of greens and supplements. Clearly mineral absorption is disrupted as i suspect is the case with lots of MSers. Right now im working on detoxing heavy metals which is very well known for disrupting mineral absorption....
Re: Vitamin D deficient....again!
Posted: Sun Jul 13, 2014 7:42 am
by want2bike
Sorry you have problems absorbing the vitamins and minerals which give us good health. People with MS and other disease often have gut issue which prevents their bodies from absorbing the necessary nutrient for good health. I followed a detox program which worked well for me. Hoping you have the same experience and get your health back.
There are all kinds of theories about vitamin d. I have tried a megadose protocol which helped improve my symptoms, but tested carefully while I was doing it to determine my serum levels. There's a report that comes with a d3 supplement that I purchased that was very informative regarding the benefits of vitamin d for overall health and certain conditions. Of course, you have to buy the supplement to get the ebook, but it's a quick read and completely worth it.
Big pharma has known about the importance of vitamin d in all autoimmune disease for a long time, but it was clear where there interests were. There are numerous studies on benefits of vitamin D at high doses (for those with autoimmune conditions) or lower maintenance doses for those who are looking for preventative care. Just dont expect Big Pharma to be pushing the investigations.
Its very likely that Vitamin D is in high doses is far more effective than the basic CRAB drugs. Its a worrying thought both for MS sufferers, and for Big Pharmas profits.
Re: Vitamin D deficient....again!
Posted: Sun Jul 13, 2014 1:52 pm
by mshealth
I agree with Family Elder. I've had great results following a megadosing program where I cycle up, stay at a certain level and then cycle down. I've done it twice so far and am beginning a new cycle in hopes of reaping further improvement of my symptoms.
Re: Vitamin D deficient....again!
Posted: Sun Jul 13, 2014 3:41 pm
by NHE
zjac020 wrote:Its very likely that Vitamin D is in high doses is far more effective than the basic CRAB drugs. Its a worrying thought both for MS sufferers, and for Big Pharmas profits.
Pierrot-Deseilligny et al. 2012 reported that every 10 nmol/L increase in 25-OH-D level, up to 110 nmol/L, was associated with a reduction in the relapse incidence rate of 13.7%.
A mere 30 nmol/L increase in 25-hydroxy vitamin D3 puts it in the efficacy range of interferon beta1a with a 41% reduction in relapses. The side effects are nonexistent and the cost is spit in a hurricane in comparison.
Note: 110 nmol/L = 44.1 ng/mL. Divide by 2.496 to convert nmol/L to ng/mL.
