Hi Melanie,
Gabapentin is used to treat nerve pain from herpes family viruses like shingles.
Oxycodone is a synthetic opoid to treat pain. It has a lot of side effects (see -
https://en.wikipedia.org/wiki/Oxycodone)
Cymbalta is a brand name for duloxetine which is a reuptake inhibitor antidepressant . This means they are targeting neurotransmitters in the hope that they hit the right one. That is a very broad brush approach to take.
Zoloft (Sertraline) is also a reuptake inhibitor that selectively targets serotonin, a neurotransmitter. If he was an obsessive-compulsive, had a major depressive disorder or extreme anxiety it would be a useful(?) treatment. (see
https://en.wikipedia.org/wiki/Sertraline )
Diclofenac is a non steroidal anti-inflammatory. I hope he has low blood pressure as it can cause hypertension as it can be supplied either as a potassium or a sodium salt. Voltaren also is Diclofenac.
So your husbands doctors are treating him for pain as though he has a herpes family outbreak but not with an antiviral to control the outbreak (eg valacyclovir).
They are potentially elevating his blood pressure with Diclofenac.
They are doping him up with opoids. They are randomly firing shots at neurotransmitters, obviously without understanding they all do different things.
Tecfedira is a rebranded dimethyl fumarate originally called BG 12 and had some application in the treatment of psoriasis. It's action in the treatment of MS is unknown but it is assumed to extend the time between attacks by modulating the T cells Th1 and Th2.
It has a black flag from the FDA (see -
http://www.fda.gov/Drugs/DrugSafety/ucm424625.htm ) I do hope the doctors conducted the required screening recommended by the FDA but I doubt it.
Can I urge you to find a completely unrelated group of medical advisors? This is a machine gun approach at its worst. Doctors work in clusters of referees. Get away from this one.
There are plenty of ideas in these pages but just be careful how you unwind this collection in case you trigger an adverse event.
My story, for what it's worth, is here -
http://www.thisisms.com/forum/regimens- ... 24019.html
Regards,