This Is MS Multiple Sclerosis Knowledge & Support Community

i agree it's fascinating! that's my word of the year i think. was that a typo where they were quoted 1,25dihydroxyvitamin (as in they didn't specify D3?)

anyway yes that is the active metabolite after the second hydroxylation, the one called calcitriol, which is the cease-fire chemical for the immune system. love it!

Please, please. no more bloody Vit D posts - I only wanted to know how much to take! The tablets arrived today and I have started (4,000 IUs a day). If you have led me up the garden path with this Vit D stuff Jimmy, you'll be dealing with my lawyer and I'll be seeking repayment of the £12.89 I have spent on the four bottles of 100 tablets.

Ian

Mushrooms might be the way to go

They are very low in calories, a source of B vitamins, good for your body's antioxidant system, available in more than 3,000 varieties in North America alone and taste great: These are just some of the reasons to love mushrooms.

In addition, researchers are trying to determine if exposure to sunlight increases the vitamin D content in mushrooms, which may make them useful in boosting the body's immune system response and disease resistance. In some tests, a standard-size serving of white button mushrooms exposed to sunlight for five minutes post-harvest contained 869 percent of a person's daily value for vitamin D.


From chanterelles to shiitakes, mushrooms have woody, fruity, earthy and sweet flavors to suit any taste. If you are looking for alternatives to ground meat in recipes, try diced creminis or buttons, while steak fans can try grilled portabellas.

http://www.nbc5i.com/health/10272673/detail.html

hey there just kind of doing an update poll on this thread...

how much vit d3 are folks taking per day since we had this discussion?
how do you blend it with or separate it from other supplements in your regimen?
would you say subjectively that your supplementation has slowed progression any?
have you noticed any particular new symptoms since you started supplementing vit d3?
if so, what type of issue?

3,000 iu's a day of d3 in the Summer, 5,000 iu's a day in the Winter. half in the morning the other half in the evening with my other supplements, symptom feel since I started BBD and supplements.

thanks for answering dave.

symptom feel since I started BBD and supplements

better? hopefully?

what all do you take besides the d3? do you take certain things at certain times of day? in any particular combinations?

Symptom FREE since I started BBD and supplements! I take all the supplements recommended by the BBD Best Bet Diet. And I must say the vitamin d was the hardest one to figure out. It took me over two years with having my vitamin d level checked ever 6 months to find the dosage level that was right for me. Started out taking too much in the Summer not enough in the Winter. I just take 1/2 the supplements in the morning with breakfast and the other 1/2 at night with dinner.

that's great. i got symptoms because i wasn't paying attention to certain things, but i know BBD is on top of a few things i ignored at first. resolving now. awesome to hear dave! hopefully one day i'll get there too stupid oven mitts grr..

Jimmylegs wrote:hey there just kind of doing an update poll on this thread...

how much vit d3 are folks taking per day since we had this discussion?
how do you blend it with or separate it from other supplements in your regimen?

Over several years I worked my way up from 260 IU to 400 IU to 800 IU and then was at 1000 IU for another year as I continued to learn more about the potential benefits from vitamin D. I had some problems and a urinalysis indicated a presence of calcium oxylate crystals. The Mayo Clinic's website suggested that this put me at risk for a kidney stone and that the presence of calcium oxylate crystals could be due to too much vitamin D. As a result, I'm now back at 200 IU and taking a blended supplement which has calcium, magnesium, and zinc.

NHE

thanks for that NHE! when you noticed the calcium issues, were you only taking d3 without the calcium, magnesium, and zinc?
i definitely benefited from adding magnesium to my day, at a diff time from the d3-cal-mag-zinc blend i had been taking prior. something to consider if you feel there would be any merit in your scenario
thanks for answering!

Jimmylegs wrote:when you noticed the calcium issues, were you only taking d3 without the calcium, magnesium, and zinc?

The 1000 IU D3 tablets I was taking had 233 mg of Ca2+ in them and no Mg2+ nor Zn2+.

On an additional note, I've had two family members that have struggled with kidney stones and I didn't want to be the third so I felt strongly that it was best to proceed with caution in my case.

NHE

so interesting. wise to take precautions. when i was regularly taking high dose vitamin d3 (which i will do again but with better information to hand this time) i would try to take more of my calcium-magnesium-zinc blend to match. they would make my back ache, which i took as a sign that i was running too many minerals through. so i eased off.
after that exp, your mention of calcium and kidney stone risk rang bells. after investigating whether magnesium is protective against kidney stones...

"Magnesium may help prevent calcium crystallising in the kidneys to create kidney stones."

followed by the abstract hunt in support of that claim...
http://www.ncbi.nlm.nih.gov/pubmed/3282851

Dis Mon. 1988 Apr;34(4):161-218.
Magnesium metabolism in health and disease.
A large segment of the U.S. population may have an inadequate intake of magnesium and may have a chronic latent magnesium deficiency that has been linked to atherosclerosis, myocardial infarction, hypertension, cancer, kidney stones, premenstrual syndrome, and psychiatric disorders.

http://www.ncbi.nlm.nih.gov/pubmed/3282851

Magnesium status of patients with renal stones and its effect on urinary citrate excretion
Objectives: To assess the magnesium status and its effect on urinary citrate excretion in patients with renal stones, as they have a low muscular magnesium content.
Results: Nine of the patients with renal stones were magnesium deficient, as were six normal subjects from the same area...
Conclusions: ...The increase in urinary citrate excretion after magnesium supplementation suggests that magnesium is important in renal stone formation, through its effect on citrate metabolism.

http://cat.inist.fr/?aModele=afficheN&cpsidt=2068785

Potassium-magnesium citrate is an effective prophylaxis against recurrent calcium oxalate nephrolithiasis.
Purpose: We examined the efficacy of potassium-magnesium citrate in preventing recurrent calcium oxalate kidney calculi...
Conclusions: Potassium-magnesium citrate effectively prevents recurrent calcium oxalate stones, and this treatment given for up to 3 years reduces risk of recurrence by 85%.

so, i've learned that magnesium and zinc need to go in in significant amounts to balance the d3/calcium intake. i've also seen the error in taking them all at the same time in combination. yes you can do that, but some mag and zinc have to go in on their own. interesting!