Myelin repair?
Posted: Fri Jun 08, 2007 2:14 pm
This should open a can of worms. What are thought to be the best ways to promote myelin repair?
Thanks,
Lars
Thanks,
Lars
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Hi Lars,Lars wrote:Where do you find this stuff?
Most of those peer review articles are as precise as possible specifically because they expect their work and words to be publicly critiqued by their peers.Lars wrote:Fairly wordy
I guess that's why I included the link to the article even though I knew you were looking for things that you could do to preserve and restore myelin right now.Lars wrote: but it seems reducing lesions is key before re-myelination can occur, no?
I agree. It might sound contrary but I'm convinced that Tovaxin can stop the disease process and hopeful that I'm not wrong.Lars wrote: Another "yippee" for Tovaxin.
Ha! Don't get me going. I'm counting the days until that lunatic gets evicted from the Whitehouse so that we can see what the next lunatic brings. I've nothing morally against using embryonic stem cells but a lot of people who do have things all tied up. I think it's time to forgo that and find ways to do what we need to with adult stem cells. Things are showing that it's not only possible but in many (important) ways using your own stem cells is better.Lars wrote:We always seem to end up at the stem cell place. Got any pull with the white house?
Well, maybe first somebody should find out why lesions occur. What if MS is found to be a neurodegenerative disease and demyelination really would be caused by axonal degeneration (as suggested by some researchers)? In that case halting demyelination and promoting remyelination would have an effect only on reverseable disability. Permanent disability caused by slow neurodegeneration would still progress.Lars wrote:Fairly wordy but it seems reducing lesions is key before re-myelination can occur, no?
Hi Finn,finn wrote:What if MS is found to be a neurodegenerative disease and demyelination really would be caused by axonal degeneration (as suggested by some researchers)? In that case halting demyelination and promoting remyelination would have an effect only on reverseable disability. Permanent disability caused by slow neurodegeneration would still progress.
Bob could you just explain how mylein reactive t cells are different in people with RRMS as opposed to SPMS or PPMS. When you shift from one to the other do things change about how you are being attacked or is it just the frequency and severity that changes.Considering the results they've been finding, I don't see how those results could do anything but prove that, at least in RRMS, removing the myelin reactive T cells from circulation has a profound effect on lesion formation and disability progression