Hormone Study - understanding/translation problem
Posted: Tue Jun 12, 2007 2:16 pm
Hi,
could someome please help me to understand the results of that study, I think I have problems with the translation:
Link PubMed
The way I understand it one sentece confilicts with the other:
When women with lower testosteron have a higher lesion cound and higher disablity, then this would not be a "positive correlation", but a "negative correlation".
How about men? Does the study say that the higher the oestradiol, the higher the brain damage (ie lesion cound / atrophy etc).
That would contradict the findigs of this study:
Link PubMed
Thanks!
--Frank[/b]
could someome please help me to understand the results of that study, I think I have problems with the translation:
Link PubMed
RESULTS: Serum testosterone was significantly lower in women with MS than in controls. The lowest levels were found in women with a greater number of gadolinium enhancing lesions. A positive correlation was observed between testosterone concentrations and both tissue damage on MRI and clinical disability.
In men, there was a positive correlation between oestradiol concentrations and brain damage.
The way I understand it one sentece confilicts with the other:
When women with lower testosteron have a higher lesion cound and higher disablity, then this would not be a "positive correlation", but a "negative correlation".
How about men? Does the study say that the higher the oestradiol, the higher the brain damage (ie lesion cound / atrophy etc).
That would contradict the findigs of this study:
Link PubMed
Thanks!
--Frank[/b]