McAlpine's 4th edition
Posted: Wed Sep 19, 2007 12:49 pm
I thought some of you might find Section 3, chapter 8, heading "THE SPECTRUM OF DISORDERS MIMICKING MULTIPLE SCLEROSIS", subheading "DISEASES THAT MAY CAUSE MULTIPLE LESIONS OF THE CENTRAL NERVOUS SYSTEM AND ALSO OFTEN FOLLOW A RELAPSING-REMITTING COURSE" written by David Miller and Alastair Compston.
Of course the book goes into details of the diseases but I have to type all this so I'm just giving the disease names.
PLEASE KEEP IN MIND THAT WHAT LIKELY IS EVEN MORE IMPORTANT IS THE INFORMATION I DIDN'T INCLUDE AND WHICH OFTEN INCLUDES REASONING WHY THESE DISEASES CURRENTLY WOULDN'T BE MISTAKEN FOR MS
Acute disseminated encephalomyelitis
Acute haemorrhagic encephalomyelitis
Systemic lupus erythematosus
Anti-phospholipid antibody syndrome
Primary Sjorgren's syndrome
Behcet's disease
Central nervous system vasculitis
Systemic vasculitis with central nervous system involvement
Isolated central nervous system vasculitis
Systemic sclerosis
Susac syndrome
Noninflammatory cerebrovascular disease
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy (CADASIL)
Sarcoidosis
INFECTIONS:
Lyme borreliosis
Meningovascular syphilis
Human immunodeficiency virus (HIV)
Progressive multifocal leucoencephalopathy
Subacute sclerosing panencephalitis
Whipple's disease
Primary lymphoma of the central nervous system
Mitochondrial disease
SYSTEMATIZED CENTRAL NERVOUS SYSTEM DISEASES
Hereditary ataxias and paraplegias
Leucodystrophies
Adrenoleucodystrophy
Metachromatic leucodystrophy
Globoid cell leucodystrophy (Krabbe's disease)
Adult onset dominant leucodystrophy
Vanishing white matter disease
Hereditary adult onset Alexander's disease
Oculodentodigital dysplasia syndrome
Vitamin B12 deficiency
Myelopathy due to nitrous oxid toxicity
Cerebrotendinous xanthomatosis
Leucoencephalopathy related to glue-sniffing
Multiple system atrophy
Paraneoplastic syndromes
Coeliac disease
Myeloneuropathy from acquired copper deficiency
Cerebellar ataxia with anti-glutamic acid dhydrogenase antibodies
Motor neuron disease and its variants
ISOLATED OR MONOSYMPTOMATIC CENTRAL NERVOUS SYSTEM SYNDROMES
Structural and noninflammatory infectious spinal cord syndromes
Spinal cord compression
Cervical spondylotic myelopathy
Chiari malformation
Spinal dural arteriovenous malformation
Tropical spastic paraplegia: HTLV-1--associated myelopathy
Noncompressive progressive myelopathy
Acute spinal cord compression
Spinal cord stroke
Transverse myelitis
Acute necrotizing myelitis
Other forms of myelitis
VISUAL FAILURE There are innumerable infective, toxic or physical causes of optic nerve disease that are unlikely to be confused with multiple sclerosis. Several rare causes due to systemic disease resulting in diagnostic difficulty have already been discussed above under a number of headings.
Anterior ischaemic optic neuropathy
Lever's hereditary optic neuropathy
Central serous choroidoretinopathy
Neuroretinitis
Chronic relapsing inflammatory optic neuropathy (CRION)
Paraneoplastic optic neuritis
Progressive visual failure
Sensory symptoms
Central pontine myelinolysis
Of course the book goes into details of the diseases but I have to type all this so I'm just giving the disease names.
PLEASE KEEP IN MIND THAT WHAT LIKELY IS EVEN MORE IMPORTANT IS THE INFORMATION I DIDN'T INCLUDE AND WHICH OFTEN INCLUDES REASONING WHY THESE DISEASES CURRENTLY WOULDN'T BE MISTAKEN FOR MS
Acute disseminated encephalomyelitis
Acute haemorrhagic encephalomyelitis
Systemic lupus erythematosus
Anti-phospholipid antibody syndrome
Primary Sjorgren's syndrome
Behcet's disease
Central nervous system vasculitis
Systemic vasculitis with central nervous system involvement
Isolated central nervous system vasculitis
Systemic sclerosis
Susac syndrome
Noninflammatory cerebrovascular disease
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy (CADASIL)
Sarcoidosis
INFECTIONS:
Lyme borreliosis
Meningovascular syphilis
Human immunodeficiency virus (HIV)
Progressive multifocal leucoencephalopathy
Subacute sclerosing panencephalitis
Whipple's disease
Primary lymphoma of the central nervous system
Mitochondrial disease
SYSTEMATIZED CENTRAL NERVOUS SYSTEM DISEASES
Hereditary ataxias and paraplegias
Leucodystrophies
Adrenoleucodystrophy
Metachromatic leucodystrophy
Globoid cell leucodystrophy (Krabbe's disease)
Adult onset dominant leucodystrophy
Vanishing white matter disease
Hereditary adult onset Alexander's disease
Oculodentodigital dysplasia syndrome
Vitamin B12 deficiency
Myelopathy due to nitrous oxid toxicity
Cerebrotendinous xanthomatosis
Leucoencephalopathy related to glue-sniffing
Multiple system atrophy
Paraneoplastic syndromes
Coeliac disease
Myeloneuropathy from acquired copper deficiency
Cerebellar ataxia with anti-glutamic acid dhydrogenase antibodies
Motor neuron disease and its variants
ISOLATED OR MONOSYMPTOMATIC CENTRAL NERVOUS SYSTEM SYNDROMES
Structural and noninflammatory infectious spinal cord syndromes
Spinal cord compression
Cervical spondylotic myelopathy
Chiari malformation
Spinal dural arteriovenous malformation
Tropical spastic paraplegia: HTLV-1--associated myelopathy
Noncompressive progressive myelopathy
Acute spinal cord compression
Spinal cord stroke
Transverse myelitis
Acute necrotizing myelitis
Other forms of myelitis
VISUAL FAILURE There are innumerable infective, toxic or physical causes of optic nerve disease that are unlikely to be confused with multiple sclerosis. Several rare causes due to systemic disease resulting in diagnostic difficulty have already been discussed above under a number of headings.
Anterior ischaemic optic neuropathy
Lever's hereditary optic neuropathy
Central serous choroidoretinopathy
Neuroretinitis
Chronic relapsing inflammatory optic neuropathy (CRION)
Paraneoplastic optic neuritis
Progressive visual failure
Sensory symptoms
Central pontine myelinolysis