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I had an appt with my neuro yesterday we had been discussing changing my therapy due to the depression side effects I get from my Avonex. Currently I'm on Avonex and pulse roids and this has worked very well for me since switching from Copaxone. He mentioned Tysabri which I'm not currently comfortable with at this time. He mentioned the only other options he is thinking about considering in my case would be Cellsept & Copaxone or Cellsept & Pulse Roids. Does anyone have any experience or knowledge about these two combo therapies? Any feedback back would be greatly appreciated.