Neurologist Dan Milder's SP & PP treatment Hypothesis
Posted: Tue Dec 11, 2007 6:59 pm
I accidental flicked onto a "press club" interview on TV of this doctor who thinks he MAY have found a possible treatment for SP & PP MS. He was very reasonable (he was coming across as arrogant, but it could of been misdirected anger) and all he was saying is that he thinks it should be investigated, he is not saying its an absolute truth. He seemed a little upset that considering there is no real treatment for these patients, an investigation into the results he has seen was called for. He didn't appear interested in running the trials himself, but was almost begging that a trial be run.
The following page is a copy of a Time magazine article ==> http://www.geocities.com/Athens/7720/time.htm
The following page is a copy of a Time magazine article ==> http://www.geocities.com/Athens/7720/time.htm
Neurologist Dan Milder was running out of ideas on how to treat one of his multiple sclerosis patients. Diagnosed less than two years ago, "Samantha" was going down fast. Her vision was blurred and she was unable to see color; she was incontinent and incoherent, and her balance was so poor she was confined to a wheelchair
Milder adjusted her drug regimen, combining a new MS drug with an older one. Her response stunned him. Within weeks, she was mentally sharper and her vision had improved. Within months, she was able to jog. Incredulous, Milder put another patient onto a similar program. Again the results were impressive. He tried it on a third, also with success.
There is more, the whole article is worth a read. I think the drugs involved are the combination of Azathioprine and interferon beta-lb.Exactly why these drugs seem to work, Milder isn't sure. But he theorizes that the onset of progressive MS, rather than being an endpoint for worthwhile treatment, may in fact be a window for a more effective drug assault that gives myelin a chance to regenerate.