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A big question in MS is the connection (if any) between relapses and disability (long term). Trials involving drugs which are very effective at stopping / reducing relapses (Campath, Mitoxantrone etc) should provide answers as to whether substantially reducing relapses has long term benefits (such as substantially slowing down disability / stopping the progression of disability). The following research examines the relationship of relapses and disability.

Ian

http://www.msif.org/en/research/ms_rese ... _disa.html