This Is MS Multiple Sclerosis Knowledge & Support Community

Lyon,

I've always regarded you as a parasite - sucking the life out of a once great MS website. Even Arron has thrown himself off the Golden Gate Bridge out of desperation. NHE has upped his dose of anti-depressants as his attempts to rein in your posts have failed. But you and your like may be of some use after all. Leeches may be a future weapon against MS.

http://www.mstrust.org.uk/news/recentst ... sp?id=2131

I just read a story today on medicalnewstoday.com about proteins being the possible cause of Parkinson's disease. We already know that a protein is being blamed for Alzheimer's disease.

Maybe a treatable protein really is the cause of MS. How great would that be??

gwa

Prof Steinman says that tests could start "Within the next year or so, as they are already approved drugs with known toxicity profiles."

I like it when we don't have to wait forever to know if they will be effective or not. The quicker the tests start, the better for us.

Judie

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This definitely steers us back towards the, " MS as a vascular disease", theory. Fibrinogen, (a protein involved in blood clotting), has been identified previously as being involved in the MS process and I seem to recall we had some threads on the subject. Also the notion that these clotting proteins shoehorn open the tight junctions between endothelial cells and allow blood products into the brain sounds like a prime candidate for the cause of a leaky blood brain barrier.
Sounds as if good progress has been made toward stopping the harmful effects of these proteins without interfering with the clotting process itself:

http://www.sciencedaily.com/releases/20 ... 105436.htm

Bob, if you gained your Ph.D. on British culture from American television you will be well aware that we all live in country mansions, have a butler, talk like the Queen or the Beatles, and have bowler hats surgically implanted at puberty.
I regret to inform you that this is only true of Ian.