Diagnosis help
Posted: Mon Dec 07, 2009 3:58 pm
I was diagnosed with MS 10 days ago.
Symptoms: double vision 6 weeks ago, optic neuritis 11 days ago, both improved since, not totally gone. I also experienced some ~ slurred speech 2 y. ago, untreated Lyme disease 9 y. ago.
My medical testing results so far:
[translated from another language, by myself]
Even if my Lyme borelliosis result, IFT - IgG: 1:64, is interpreted as negative, and result is not to be doubted - online.wsj.., anyone know of some other bacterial tests I should take ?
One can get similar symptons, as well similar lesions, afaik, as Bartonella, Brucella canine, ... although I don't remember any fever..
How long did it take you to get your MS diagnosis, how definite MS would you think I am ?
My next doctor visit is in two days, any suggestions which questions should I ask, additional tests I should take ?
No evoked potentials testing was done [yet?].
I'd prefer not get treated with wrong drugs.
Tnx for any reply
Symptoms: double vision 6 weeks ago, optic neuritis 11 days ago, both improved since, not totally gone. I also experienced some ~ slurred speech 2 y. ago, untreated Lyme disease 9 y. ago.
My medical testing results so far:
[translated from another language, by myself]
Code: Select all
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1. sample: Liquor
Treponema pallidum, antibodies VDRL-RPR: nonreactive
Treponema pallidum, antibodies TPHA: negative
2. sample: Serum
Treponema pallidum, antibodies VDRL-RPR: nonreactive
Treponema pallidum, antibodies TPHA: negative
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intrath. synthesis IgG 20,59% [H]
intrath. synthesis IgA 0
intrath. synthesis IgM 0
S-Glucosys 4,2 mmol/L (normal 3,6-6,1)
Lc-Albumin (immunoc.) 343
Lc-IgG 67,70 mg/L
Lc-IgA 4,86 mg/L
Lc-IgM 0,53 mg/L
Quotient Alb (10E3) 6,86
Qalb ref. value 6,2
Quotient IgG (10E3) 6,39
Q lim(IgG) 5,07
Quotient IgA (10E3) 1,78
Q lim(IgA) 3,35
Quotient IgM (10E3) 0,40
Q lim (IgM) 1,56
S-Albumin (immuno) 50 g/L (ref 35-52)
inflammation
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1. Sample: Serum
Lyme borelliosis - immunoflourescent test without absorbtion
IFT - IgM: negative
IFT - IgG: 1:64
( [border?] titer was 1:256 )
2. Sample: Liquor
Lyme borelliosis - immunoflourescent test without absorbtion
IFT - IgM: negative
IFT - IgG: negative
( [border?] titer was 1:16 )
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(test) (result) (units) (orientative ref. value)
S-IgG 10,60 g/L ( 6.90 - 14.00 )
S-IgA 2,73 g/L ( 0.70 - 4.10 )
S-IgM 1,32 g/L ( 0.30 - 2.40 )
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1. sample: Liquor
Tick-borne meningoencephalitis: negative
Mumps: negative
Herpes simplex 1+2: negative
Enteroviruses: negative
Polioviruses (pool): negative
Varicella zoster: negative
2. sample: Blood (for serologic research)
Tick-borne meningoencephalitis: 1:20
Mumps: negative
Herpes simplex 1+2: negative
Enteroviruses: negative
Polioviruses (pool): negative
Varicella zoster: 1:20
--------------
Test results of cerebrospinal liquor and serum for oligoclonal bands
Liquor: positive
Serum: negative
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MRI: demyelinating lesions
Numerous T2 hyperintensive oval lesions, largest one is 2.6 x 2.3cm (1.02" by 0.90"), numerous lesions in corpus callosum and beside it, some are also on T1 hypointense. Contrast medium colorized ring visible in mentioned largest lesion, as well in lesion next to
occipital horn of the left lateral ventricle. Numerous lesions in pons and medulla oblongata - mostly right side.
( I believe most of my lesions are in right hemisphere, and I usually sleep on right side of my head - are such results common ? )
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Motoric tests were fine, slight tremor on the right in finger-nose test, reflexes slightly better on left side.
Euphasic, no meningeal signs.
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( blood test before Medrol was ok, low lymphocytes % [L] 19.7 (ref 20-50), lymphocytes num. 1.1 [ref 0.8-5] )
I received 3 Solu-Medrol (methylprednisolone) infusions [10,9,8] days ago.
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local lab blood test, taken 5 days after last Medrol infusion:
S-Uric acid (ref 150-480) 328 µmol/L
S-Fe (ref 10.7-28.6) 27.9 µmol/L
S-Calcium (ref 2.1-2.6) 2.4 mmol/L
S-Magnesium (ref 0.7-1.10) 0.95 mmol/L
S-Ferritin (ref 30-400) 113.9
S-Cortisol (ref am 171-536, pm 64-327) 560.9 [H] ( 11:27:09 am, almost pm )
still waiting for Vitamin D3 (25-OH tnx jimmylegs), EBV-EBNA-1, et al
Lower S-Uric acid levels are more common in MS, according to http://en.wikipedia.org/wiki/Uric_acid, but Methylprednisolone increases Uric acid levels, as well does B-12 - which I took daily 4 previous days, not sure how much effect these might have had.
Any ideas how long should I have waited before taking that test, or how long before any blood test should one have stopped taking any pills ...
One can get similar symptons, as well similar lesions, afaik, as Bartonella, Brucella canine, ... although I don't remember any fever..
How long did it take you to get your MS diagnosis, how definite MS would you think I am ?
My next doctor visit is in two days, any suggestions which questions should I ask, additional tests I should take ?
No evoked potentials testing was done [yet?].
I'd prefer not get treated with wrong drugs.
Tnx for any reply