Tryptophan raises beta-endorphin production
Posted: Mon Jan 23, 2006 2:42 am
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It strikes me Stavros that your “thinking out loud” parallels some of the ideas in this hypothesis of MS. It may be pertinent as well to Lynda Carol’s pursuit and interest in “high insulin levels” in people with MS. The sugars and carbohydrates I love are definitely out of my diet because of my sensitivity to them. It’s a bad combo with my MS for sure and stress is worse, without a doubt.This hypothesis is supported by the findings in chronic MS patients of significantly diminished adrenal cortisol reactivity to insulin-induced hypoglycemia which is considered a stress response mediated through the 5-HT system. Consequently, since patients with MS exhibit an abnormal response to stress it follows that increased tryptophan availability through dietary supplementation would diminish their vulnerability to psychological stress. Additionally, if sustained or repeated stress contributes to progression and clinical deterioration of the disease then chronic tryptophan supplementation also may halt its progression.