This Is MS Multiple Sclerosis Knowledge & Support Community

ASCEND study to evaluate the effectiveness of Tysabri in secondary progressive MS



Biogen Idec today announced a global Phase 3b study, ASCEND, that is being conducted to evaluate the effectiveness of Tysabri as a treatment for secondary-progressive multiple sclerosis (SPMS). According to the National Multiple Sclerosis Society, approximately half of all people initially diagnosed with relapsing-remitting multiple sclerosis (RRMS) - the most common form of multiple sclerosis (MS) - will transition to SPMS within 19 years.

Patients with RRMS typically experience unpredictable relapses; the time between relapses is characterised by full or partial recovery and a lack of disease progression. SPMS is characterized by a steady progression of nerve damage, symptoms and disability, but the exact reasons for the progression are unknown. The potential for greater disease burden in SPMS typically includes decreased mobility, impaired activities of daily living, loss of independence and reduced quality of life.... Read More - http://www.msrc.co.uk/index.cfm/fuseact ... ageid/1768

The ASCEND study is part of the ongoing commitment of both Biogen Idec and Elan to find ways to improve the well-being of patients with multiple sclerosis.

After reading the two recent threads on ThisIsMS (ex pharma sales rep and the industry actions of drug companies) I have a very difficult time putting one ounce of credibility in that statement!!