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Hello everybody
i should be soon on Tysabri, i am aware of the risk and seconday effects(headache,...) of it.

MS Society of Canada also says that the infusion is painful in itself:
"A person getting an intravenous infusion will probably feel a sharp pain or some discomfort when the needle penetrates the skin and vein, but then the discomfort should subside as the infusion proceeds. There may also be discomfort when the infusion needle is removed and the site may or may not feel sore for a day or so."
(http://www.mssociety.ca/en/research/res ... ysabri.htm)

Could any of you under tysabri tell me whether infusion is really painful?

My Solumedrol infusions have never been painful, i don't even feel the neeedle when it penetrates my vein(nurses always tell me that my veins are wonderful), that's why i don't understand why it should be different with tysa.
Thanks for explaining this.

superman wrote: "A person getting an intravenous infusion will probably feel a sharp pain or some discomfort when the needle penetrates the skin and vein, but then the discomfort should subside as the infusion proceeds. There may also be discomfort when the infusion needle is removed and the site may or may not feel sore for a day or so."

I don't remember any pain when I had my one Tysabri infusion years ago. Certainly nothing more than when getting blood drawn for testing, or for an interferon injection. Don't worry. Take an Advil or Tylenol an hour before if you think it might hurt.

I had 6 Tysabri infusions and there was absolutly no pain at all...

I've never had an infusion, even for steroids. But I would guess the same people would say the same for any injection. As for relieving the prick, or fear of the prick, try an emla patch. It completely deadens the skin; after about an hour+. Its normally recommended for minor surgery.