Posted: Sat Sep 19, 2009 2:21 pm
Bob,
I'm going to have to respectfully disagree with you ;) . I was referring to AHSCT which is the complete ablation of the immune system including the bone marrow, hence the need for transplantation afterwards. Cyclophosphamide is used as the ablative agent. I did point out in my post that HiCy and AHSCT were two different things.
Monoclonal means that all of the cells are genetic clones of each other, hence they can be tailored to target a specific antigen such as CD52.
Robin
I'm going to have to respectfully disagree with you ;) . I was referring to AHSCT which is the complete ablation of the immune system including the bone marrow, hence the need for transplantation afterwards. Cyclophosphamide is used as the ablative agent. I did point out in my post that HiCy and AHSCT were two different things.
Monoclonal means that all of the cells are genetic clones of each other, hence they can be tailored to target a specific antigen such as CD52.
Robin