Fecal microbiota transplantation
Posted: Fri Dec 06, 2013 1:13 pm
Its gross, no doubt, but the science behind "poop transplants" is starting to turn heads in the medical community. For MS it really speaks to the idea that gut bacteria makes a big difference in disease progression.
"...Whilst using FMT (fecal microbiota transplantation) to treat ulcerative colitis or constipation-predominant IBS in the Sydney clinic, serendipitous improvements in extraintestinal conditions not previously considered to be microbiota-related have also been observed. These include the virtually complete and prolonged (>15 years) normalization of previously severe multiple sclerosis symptoms in three patients whose constipation was the target of FMT,48 and progressive normalization of platelet counts in a patient with idiopathic thrombocytopenic purpura whose ulcerative colitis was successfully treated with FMT. In addition, we have also previously reported on the improvement of chronic fatigue syndrome using FMT in a long-term follow-up study. Of the 34 patients who underwent FMT and were available for follow-up, 14 (41.2%) patients obtained persisting relief and seven reported mild or gradual improvements..."
http://scholar.google.ca/scholar_url?hl ... kQgAMoADAA
"...Whilst using FMT (fecal microbiota transplantation) to treat ulcerative colitis or constipation-predominant IBS in the Sydney clinic, serendipitous improvements in extraintestinal conditions not previously considered to be microbiota-related have also been observed. These include the virtually complete and prolonged (>15 years) normalization of previously severe multiple sclerosis symptoms in three patients whose constipation was the target of FMT,48 and progressive normalization of platelet counts in a patient with idiopathic thrombocytopenic purpura whose ulcerative colitis was successfully treated with FMT. In addition, we have also previously reported on the improvement of chronic fatigue syndrome using FMT in a long-term follow-up study. Of the 34 patients who underwent FMT and were available for follow-up, 14 (41.2%) patients obtained persisting relief and seven reported mild or gradual improvements..."
http://scholar.google.ca/scholar_url?hl ... kQgAMoADAA