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Re: Optic Neuritis and possible cause for MS

Posted: Sat Nov 09, 2013 5:24 am
by Celeste485
Thank you Jimmy, I am not sure what am I going to do yet as Multiple Sclerosis is no longer a mystery disease. The lesions are caused by iron. Few months before my daughter’s first attack I ordered gummies multivitamins from Amazon but they had a lot of sugar and no iron which we are told young women need. So I bought another kind this one comes with iron. My daughter never liked them so I only was giving them to her once in a while. I don’t think she took more than 2 pills before the tingling happened. And the rest you know.
There is a reason why people with ms have low iron and why iron deposits are on the brain, iron is killing your brain people and the body naturally keeps it low to keep you alive.
I guess it’s time to celebrate.

Re: Optic Neuritis and possible cause for MS

Posted: Sat Nov 09, 2013 5:45 am
by jimmylegs
here's something you might want to consider

http://www.thisisms.com/forum/chronic-c ... tml#p57772 (2009)

Zinc Deficiency-induced Iron Accumulation, a Consequence of Alterations in Iron Regulatory Protein-binding Activity, Iron Transporters, and Iron Storage Proteins
http://www.jbc.org/cgi/content/full/283/8/5168
One consequence of zinc deficiency is an elevation in cell and tissue iron concentrations. To examine the mechanism(s) underlying this phenomenon, Swiss 3T3 cells were cultured in zinc-deficient (D, 0.5 μm zinc), zinc-supplemented (S, 50 μm zinc), or control (C, 4 μm zinc) media. After 24 h of culture, cells in the D group were characterized by a 50% decrease in intracellular zinc and a 35% increase in intracellular iron relative to cells in the S and C groups. The increase in cellular iron was associated with increased transferrin receptor 1 protein and mRNA levels and increased ferritin light chain expression. The divalent metal transporter 1(+)iron-responsive element isoform mRNA was decreased during zinc deficiency-induced iron accumulation. Examination of zinc-deficient cells revealed increased binding of iron regulatory protein 2 (IRP2) and decreased binding of IRP1 to a consensus iron-responsive element. The increased IRP2-binding activity in zinc-deficient cells coincided with an increased level of IRP2 protein. The accumulation of IRP2 protein was independent of zinc deficiency-induced intracellular nitric oxide production but was attenuated by the addition of the antioxidant N-acetylcysteine or ascorbate to the D medium. These data support the concept that zinc deficiency can result in alterations in iron transporter, storage, and regulatory proteins, which facilitate iron accumulation.

Re: Optic Neuritis and possible cause for MS

Posted: Sat Nov 09, 2013 5:52 am
by jimmylegs
these are some great gummies http://www.nordicnaturals.com/en/Produc ... rodID=1411
kids need 4 per day. my brother has both his boys on them (finally) and they have not been sick in ages.
I wonder if you used gummies like that to prevent zinc induced iron dysregulation, plus used a low gluten, iron/zinc-rich diet with plenty of vitamin C, what the improvements could be like.
the blood work is always the key. to make sure everything is done safely.

Re: Optic Neuritis and possible cause for MS

Posted: Sat Nov 09, 2013 6:47 am
by Celeste485
Hey Jimmy, I haven't slept all night, I will read it all after I wake up but after just scanning the article I have a question, what happens when the iron doesn't bind to any cell? Isn't it better if it binds to something rather than floating around and maybe penetrating the brain barrier? But I have oysters waiting, we can consume them at a moment notice as long as you can tell me the zinc doesn't release the iron and make it worse.
Jimbooo, aren't you happy ms is no longer a mystery disease? Now we can move on to the cure part. I am all for it. You?

Re: Optic Neuritis and possible cause for MS

Posted: Sat Nov 09, 2013 10:23 am
by jimmylegs
re concern for the BBB, there's this aspect to consider:

Zinc Deficiency Exacerbates Loss in Blood-Brain Barrier Integrity Induced by Hyperoxia Measured by Dynamic MRI
http://www.ncbi.nlm.nih.gov/pubmed/10654621
"zinc deficiency resulted in a significant increase in both kPSρ and ve, indicating a severely disturbed BBB."

the human body wants to do things right - it just has to be provided with the tools it needs, and then status can be monitored to make sure things are working as intended.

Re: Optic Neuritis and possible cause for MS

Posted: Sun Nov 10, 2013 7:04 am
by teeli30
I was diagnosed in 2/11 with M.S. I have optic neuritis along with the memory loss . Now I believe that there are many of toxins that can contribute to our disease. I had my MRI and was told I tested positive for multiple lesions . Yes, I had 11 on my brain affecting mainly the right side of my body. I experienced every known symptom on the exception of temp. Blindness. I went through the lumbar puncture and 3 lesions appeared to be on my spine. A couple of months later I had an MRI w/wo contrast results show two new lesions. After Copaxone treatment for almost 8 mos, my active lesions became in active and I was left with a lot of nerve damage to numerous parts of my body. So for at least 2 years I experienced the MS attack. I wasn't able to be left alone because I had to have someone to care for me. It was crucial that the meds prescribed begin to kick in yet I had to have back up treatments sy as infusions. It was a long journey for recovery. However, I begin to relapse. Repeatedly. So finally it came to my remission . I am now in 1/2012 when it shows my lesions were inactive. However, due to all my symptoms they were already there before I was clearly diagnosed. I had been experiencing these vague symptoms after the the birth of my first son. I would have never imagined having been sick because I was always pretty healthy and no other known illness. Moving to the present my dr recently took me off of the injections so in 2/13 I had another MRI done. No new activity so it's safe to say I'm free of activity. On 9/13 a new MRI was done. A new lesion has appeared so I'm hoping I don't experience another severe attack like the first one which almost left me in a wheelchair if my drs. would not have acted as fast I would be in one. The severity of my disabling has taken a toll on me and with all I have endured I have been told there's no cure only a temp. fix, I just can't understand how a disease could be undiagnosed for so long. All of the cures I believe are in the foreign country and the reason we don't have access is that the medical world would go broke. Yes I think all our answers are here on the earth but it doesn't seem to be in the the prescription bottles they give us. Just pray and God will lead the way to answer our prayers....God bless all of you who endure the symptoms of this debilitating disease...

Re: Optic Neuritis and possible cause for MS

Posted: Sun Nov 10, 2013 7:30 am
by jimmylegs
childbearing takes a heavy toll on the nutrient status of mothers. in particular, zinc levels are measurably affected during pregnancy. research has linked zinc status with optic neuropathy also. further, zinc status affects utilization of a number of other nutrients that are of consequence for ms patients, including magnesium, vit b12, vit A, and vit D. it's worth investigating. at the same time, you have to be aware that ms patients are usually low NORMAL for various nutrient tests, so your results won't stand out as being insufficient. in general you need to have high normal status in order to match levels found in healthy individuals.

Re: Optic Neuritis and possible cause for MS

Posted: Mon Nov 11, 2013 7:54 am
by Celeste485
So now that you know iron is the cause of ms let me add few things. Ms is some sort of a metabolic disease. People with ms absorb too much iron and the iron floats and attaches itself to whatever it finds. The fat loves the abdominal fat, liver, joints and in your case the myelin. Iron loves this type of fat. People who have more abdominal fat would attract the iron right after it enters the body so in these people the iron causes less damage. It’s only in those who don’t have enough parking space at the beginning that the iron ventures deeper and deeper inside. You will find it anywhere you find this soft kind of fat.
There are 2 kinds of irons, hemme in meats and non hemme in plants, breads, cereals etc... I believe based on my own observation of my daughter that it is the non hemme iron that is causing the trouble. The non hemme iron needs vitamin c to be absorbed. The vitamin c can be removed from the body but the iron that follows it cannot. The buildup of iron causes you all your problems. But many times when you’re feeling bad it could be right after eating too much vitamin c, because the body is trying to remove it asap and that can cause some symptoms as well. It does in my daughter. She coughs for example after eating strawberries.
There need to be studies in this to determine exactly the mechanism behind it but my discovery is a huge thing because if it is a mechanism behind it, this can be treatable with some medicines. If it is a genetic fault then diet will be the only thing that will work for this. I cannot provide you with any medical advice but here is the first thing I did for my daughter, I stopped giving her supplement with exception of vit. D, some cod liver and calcium. She will never take any iron supplement or high doses of vitamin c, so help me God! She will continue eat meats but the other foods will be limited and she will eat them with calcium, cheese, milk, tea to not to allow the iron in. So all I can say, hang in there. Help is on the way!

Re: Optic Neuritis and possible cause for MS

Posted: Mon Nov 11, 2013 8:01 am
by Celeste485
Correction:
In the 4th sentence should be: the iron loves abdominal fat not the fat loves abdominal fat.

Re: Optic Neuritis and possible cause for MS

Posted: Mon Nov 11, 2013 8:08 am
by Celeste485
Telli, your belly was big when you were pregnant so your iron had a place to land, now that you lost that fat, it's all over your body wreaking your life. Do not give your baby any iron supplements or vitamin c in high doses, that goes for juices as well. You don't want your baby to get sick. If you have this disease, he may have it too. It's not ms that is hereditary it's the iron metabolism. I made this mistake with my daughter and now she has MS.

Re: Optic Neuritis and possible cause for MS

Posted: Mon Nov 11, 2013 10:06 am
by jimmylegs
celeste you're going to have to start backing up your assertions with some research. pubmed is a good database. if you add pubmed to your search terms when looking for online info, and then select the 'scholarly articles' section from the top of the results, that could be useful. I highly recommend some academic reading on the zinc iron balance.

Re: Optic Neuritis and possible cause for MS

Posted: Mon Nov 11, 2013 10:18 am
by Celeste485
God, this thing goes so fast, I cannot even think straight.
I just found a cure!!!
I sent email to UCLA professor who was working on iron in the brain and he sent me email back telling me that iron is needed to repair myelin and it hit me, just like that.
I just found a cure for MS!!!
It's the hemme iron that your body needs. It's in the meat. The body takes in too much of the non hemme iron from carbs because that is the only available one when the body is in need of iron and at some point it crashes. Eventually maybe it's starting recycling the blood and cannot do any function properly. I think this is why it refuses to absorb the non hemme iron. Too much of non hemme iron causes inflammation. Because it needs the other one. It waits for the other one so it can do the job. This is why it will not absorb any of the garbage that is coming in and in the process is making you sick. You have to eat meat frequently, not a lot because the body doesn't absorb too much iron all at once. It takes iron in small parts, so meat throughout the day is the key. I am feeding my daughter now with meat first, then vegetables and then some carbs. I want to make sure the body takes the meat first and feels up on it. This will heal Multiple Sclerosis.
You need to give the body enough of the good iron, the functional iron, your life depends on it! The other one it's only there for times when the hemme is not coming to buy some time. This is why there are two kinds of irons. The hemme, absorbable one and the non hemme, the one that can only be absorbed with vit. C and with the good one. Do not take any iron supplements, they are not good for you. I hope this helps. Good luck guys!

Re: Optic Neuritis and possible cause for MS

Posted: Mon Nov 11, 2013 11:18 am
by Celeste485
Jimmy, Pubmed is a great resource center but I have established my own Pubmed now and my thread is all the proof you need. I said at the beginning of my writing that my daughter wasn't eating enough fat. 2 months after her diagnosis her MRI is the proof the fat works because her lesions from spine disappeared and the others were healing, and there was no new lesions. This proves that the extra fat, the hemme iron I fed her was helping her just like I am saying now. Now the problem is with bacterial infection which complicates things a little, but we are removing the toenail as soon as I can get the approval and all will work out well. This thread is my own personal research library and I am patenting it right now! Anyone who wants to use my information, have to pay me big bucks. You are my witnesses. :-D :-D :-D

Re: Optic Neuritis and possible cause for MS

Posted: Mon Nov 11, 2013 2:06 pm
by jimmylegs
all right peace out and good luck

Re: Optic Neuritis and possible cause for MS

Posted: Wed Nov 13, 2013 8:11 pm
by Celeste485
Jimmy, I am so sorry. You were so right about the zinc. We have real crisis here. Go to my new post and read it.