George HSCT risk factors
Posted: Sat Aug 31, 2013 8:37 pm
I was just wondering what your thoughts were on risk factors after hsct such as
When looking to all-cause mortality in a cohort of almost 1500 patients who survived 2 or more years after allo-HSCT, mortality rates remain twice as high as that of the general population among 15-year survivors of allo-HSCT, and that the survivors face challenges affecting their health and well-being. Relapse of primary disease (29%) and chronic GVHD (cGVHD; 22%) were the leading causes of premature death.3 Moreover, in patients who have survived for at least 5 years after allo-HSCT without recurrence of the original disease, life expectancy is still not fully restored. Mortality rates remained four- to ninefold higher than those expected in the general population for at least 30 years after transplantation, providing an estimated 30% lower life expectancy, regardless of current age.
How do you feel the risks measured up with the reward.
When looking to all-cause mortality in a cohort of almost 1500 patients who survived 2 or more years after allo-HSCT, mortality rates remain twice as high as that of the general population among 15-year survivors of allo-HSCT, and that the survivors face challenges affecting their health and well-being. Relapse of primary disease (29%) and chronic GVHD (cGVHD; 22%) were the leading causes of premature death.3 Moreover, in patients who have survived for at least 5 years after allo-HSCT without recurrence of the original disease, life expectancy is still not fully restored. Mortality rates remained four- to ninefold higher than those expected in the general population for at least 30 years after transplantation, providing an estimated 30% lower life expectancy, regardless of current age.
How do you feel the risks measured up with the reward.