Stem Cells in MS review
Posted: Thu Dec 04, 2008 1:36 pm
This medscape article authored by Karoussis and Kassis found here
http://www.medscape.com/viewarticle/563024_2
details the potential use of stem cells for MS. It discusses the different types of cells, studies that have been done, and the results. This paper is a REVIEW (IMHO the cadillac of papers- means somone looked extensively at a variety of other people's work on something) of cumulative research to date on the subject.
marie
http://www.medscape.com/viewarticle/563024_2
details the potential use of stem cells for MS. It discusses the different types of cells, studies that have been done, and the results. This paper is a REVIEW (IMHO the cadillac of papers- means somone looked extensively at a variety of other people's work on something) of cumulative research to date on the subject.
andA logical treatment approach to enhance neuroprotective mechanisms and to induce neuroregeneration in MS is with stem-cell transplantation.[2,3] Stem cells are a diverse group of multipotent cells.
I have been interested in the evolution of stem cell research. This paper is a great overview of what is going on. It's a little dense in some places but tell me what you think!In the current review, the various types of stem cells, which were mainly studied in animal models, will be reviewed as a potential therapeutic approach for MS. The main and common mechanisms of action of all stem cells include induction of neuroregeneration and remyelination through the activation of resident stem cells, or production of new CNS cell lineage progenitors, paralleled by local and systemic immunomodulating effects.
marie