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Posted: Sat Jan 09, 2010 8:19 am
by cheerleader
wonderful thread! Thanks for reviving it, Lyndacarol! Jeff's benefited from his evening dose of Natural Calm,- Jimmy first suggested mg to us over 2 years ago as an anti-spasm treatment. Mg is has kept spasms at bay, kept him regular, aided sleep- but there are other benefits, like acting as a natural statin, reducing C-reactive protein (CRP)-wanted to see if I could find more recent research on the endothelial benefits of mg-
In a study by our research group of a representative sample of individuals in the US [16], adults who consumed < 50% of the RDA of magnesium were found to be more likely to have elevated CRP than adults who consumed ≥ RDA (OR = 1.75; 95% CI = 1.08-2.87). Adults over age 40 with a BMI > 25 and less than half of the magnesium RDA were even more likely to have elevated CRP (OR = 2.24; 95% CI = 1.13-4.46). These results were maintained after controlling for demographic and cardiovascular risk factors. In a second cross-sectional study, we found that magnesium supplementation lowers the likelihood of elevated CRP in people with low dietary magnesium intake by 22% [17]. This observation suggests that not only does magnesium deficiency increase inflammation, but that magnesium supplementation may be a useful strategy for reduction of inflammation, especially in people with low levels of magnesium content from foods in the diet. The study also provides important epidemiologic support for the idea that it is the magnesium itself, rather than some other component of foods high in magnesium, that is responsible for the decreased likelihood of elevated CRP.
link

cheer

Posted: Sat Jan 09, 2010 6:14 pm
by CureOrBust
I believe we need to be careful when taking the statement "acting like a statin". Statins main prescription useage is as a cholesterol lowering medication. Therefore, I would hazard a guess, its this specific effect that medical people are specifically referring to.

There has been research that implies Statins benefit to MS has been because of lowering the permeability of the BBB. So, I would not expect that something said to have a "Statin like" effects, to necessarily work for MS in a similar manner; I would simply expect it to lower cholesterol.

I take 80mg Lipitor / day (and its been the best for my daily MS managements, I think), and I also take Mg Citrate to minimise any restless leg symptoms.

Another way to look at it, is that although Statins may have an Mg like effect in lowering cholesterol, the Lipitor does not have an Mg Citrate like effect at lowering restless leg symptoms.

NB: I also understand that low saturated fat diets are associated with MS diets, but that is a different path of modality.

Magnesium Citrate: is this product sufficient?

Posted: Thu Jun 10, 2010 3:35 am
by adamt
Hi,

I used to take Magnesium oxide (500mg daily) but then ;learnt m oxide is not well absorbed by the body.

So i now take Magnesium Citrate as it is meant to be the best absorbed form of magnesium.

I also take 600mg of Calcium twice daily.

But on the M Citrate label it says:


One vegicap typically provides:

Content:
Magnesium Citrate
500mg
(Elemental Magnesium
80mg)

This slightly confuses me, if i take 2 a day, am i taking 1000mg of Magnesium a day, or just 160mg?

As im taking 1200mg of Calcium daily, i need to be taking at least 600mg of Magnesium.

thanks

Re: Magnesium Citrate: is this product sufficient?

Posted: Thu Jun 10, 2010 12:30 pm
by NHE
adamt wrote:But on the M Citrate label it says:


One vegicap typically provides:

Content:
Magnesium Citrate
500mg
(Elemental Magnesium
80mg)

This slightly confuses me, if i take 2 a day, am i taking 1000mg of Magnesium a day, or just 160mg?
The tablets are correctly labeled, 500 mg of magnesium citrate provides 80 mg of magnesium.

For a more detailed explanation, magnesium citrate has the molecular formula of Mg3(C6H5O7)2. There are 3 moles of magnesium for every 2 moles of citrate (moles are the way chemists count molecules, they are like a baker's dozen, the actual number is 6.022x10^23 things per mole, things usually being either atoms or molecules). Therefore, for each mole of magnesium citrate there will be 72.92 g of magnesium and 378.22 g of citrate. The magnesium content will be 16.16% weight of the total. This figure is in agreement with the labeling on your tablets. In effect, 80 mg of magnesium is 16% of the total 500 mg of magnesium citrate.

By the way, the high percentage of citrate should not be a problem. Citrate is actually good for helping to prevent calcium oxalate kidney stones.

NHE

Posted: Thu Jun 10, 2010 12:42 pm
by adamt
Thanks NHE for the detailed reply

But if im taking 1200mg of Calcium daily, i am told it ise ssential i take 1/2 the amount in Magnesium = 600mg

And based on the actual magnesium content i would only be taking 160mg of magnesium with two 500mg mag citrate capsules.

Or is the mag citrate being 500mgx2 sufficient to take with 1200mg of calcium?

thanks

Re: Magnesium Citrate: is this product sufficient?

Posted: Thu Jun 10, 2010 1:17 pm
by NHE
adamt wrote:But if im taking 1200mg of Calcium daily, i am told it ise ssential i take 1/2 the amount in Magnesium = 600mg
What form of calcium are you taking? Does it actually supply 1200 mg of calcium or is it something like 1200 mg of calcium carbonate which would provide 480.5 mg of calcium?

NHE

Posted: Thu Jun 10, 2010 2:20 pm
by jimmylegs
at the end of the day magnesium citrate is not ideal. magnesium glycinate is better. my pills (you take 2 to get 400mg) are great, you can take plenty and it does not send you running to the toilet like mag oxide or mag citrate. however,the product i have does not specify elemental magnesium - i would have to go digging for that info.

Posted: Thu Jun 10, 2010 2:46 pm
by adamt
jimmylegs wrote:at the end of the day magnesium citrate is not ideal. magnesium glycinate is better. my pills (you take 2 to get 400mg) are great, you can take plenty and it does not send you running to the toilet like mag oxide or mag citrate. however,the product i have does not specify elemental magnesium - i would have to go digging for that info.
i see,

i have recently started using magnesium oil, as this is meant to be absorbed well.

I used 5 droplets on each arm, each leg, and on stomach/chest.

I rub the oil in, in the evening.

Would this be the most efficient form of magnesium?

Re: Magnesium Citrate: is this product sufficient?

Posted: Thu Jun 10, 2010 2:51 pm
by adamt
NHE wrote:
What form of calcium are you taking? Does it actually supply 1200 mg of calcium or is it something like 1200 mg of calcium carbonate which would provide 480.5 mg of calcium?

NHE
i take this calcium product:

http://www.hollandandbarrett.com/vf/labels/004233HB.pdf

Is this a good calcium supplement, or if not could you recommend a different one from that site please?

- i also said in my last post i use magnesium oil on my body, could that replace the need for magnesium tablets?

Posted: Thu Jun 10, 2010 7:31 pm
by jimmylegs
hi adamt,

i would need more info to answer your question. simple answer yes you can absorb magnesium thru your skin. in more detail, what form of mag oil? chloride? not 100% sure of the answer but it looks like yes it would absorb... but you have to choose mag oil [chloride (salt)] or tablet [glycinate (sweet)]. don't know enough for a conclusive answer, sry!

Re: Magnesium Citrate: is this product sufficient?

Posted: Fri Jun 11, 2010 3:05 am
by NHE
jimmylegs wrote:at the end of the day magnesium citrate is not ideal. magnesium glycinate is better. my pills (you take 2 to get 400mg) are great, you can take plenty and it does not send you running to the toilet like mag oxide or mag citrate. however,the product i have does not specify elemental magnesium - i would have to go digging for that info.
Magnesium glycinate is chelated with the amino acid glycine. The molecular formula is Mg(C2H4NO2)2·H2O (two glycines plus a water of hydration per magnesium atom) so it is 12.8% magnesium by weight. So, for example, if you're taking 1000 mg of magnesium glycinate, then you're getting 128 mg of magnesium.

NHE

Posted: Fri Jun 11, 2010 3:34 am
by adamt
this is the mag oil i use:

<shortened url>

I dilute it 50:50 with distilled water so it lasts konger.

Could this replace the need for magnesium supplements if i use it every night?

Was the calcium i showed sufficient?

thanks

Posted: Tue Aug 31, 2010 9:11 am
by jimmylegs
hi adam sorry i missed this one for so long.

i would say 2 of your calcium pills per day would be appropriate.

also, i really couldn't say if the diluted oil would be a passable substitute for pills. if you can get two large servings of dark leafy greens (cooked or raw) into you each day, that is a great start. supplements and/or oil to augment are only needed if your serum Mg level is below .9 mmol/L:

http://www.thisisms.com/ftopicp-56317.html#56317
Journal of the American College of Nutrition, Vol. 23, No. 6, 730S-731S (2004)
About the Misdiagnosis of Magnesium Deficiency
http://www.jacn.org/cgi/content/full/23/6/730S
Quote:
...In patients with Mg serum values lower than 0.9 mmol/l Mg, magnesium supplementation is recommended; for patients with values lower than 0.8 mmol/l, starting Mg supplementation is necessary. We recommend that a Mg serum value of 0.9 mmol/l Mg be considered as the lower reference limit, in evaluating symptoms or diseases suspected as being associated with Mg deficiency. In this case, Mg has to be used as a first choice therapy. When symptoms of the MDS are found, patients with serum values of less than 0.8 mmol/l Mg, or better 0.9 mmol/l Mg, ... [not automatically] normomagnesemic.
hope that helps!

jimmylegs

Posted: Fri Sep 03, 2010 1:43 am
by shye
Just came across this thread--
Adam,

the glycinate form of mg that I take is Doctor's Best, and it specifically states on the label the amt of elemental mg that you get per tablet (100 per tablet).

Magnesium Potassium Aspartate supplement - ok for MS/CCSVI?

Posted: Fri Nov 05, 2010 7:47 am
by adamt
Hi,
Im thinking of taking this Magnesium Potassium Aspartate supplement as it has a range of different forms of Magnesium, as currently i only take 400mg of Magnesium oxide with 800mg Calicum (aboth in one tablet) every day
this product - <shortened url>


this is the Magnesium Potassium Aspartate im looking at buying:

<shortened url>


So i was wondering if anyone knew if Potassium is in anyway bad for MS patients or CCSVI patient,

i have SPMS and have CCSVI - IJVs, and May Thurner

thank you