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My 20 year old daughter just started the Minocycline a month ago but is now complaining of severe heartburn, upset stomach, etc. Does anyone on the Minocycline have this problem & what have you used to help. Over the counter antacids don't work. Taking the Minocycline 100 mg x2 a day, she is also taking aspirin x2 a day (was on provigil but was told to try the aspirin for fatigue), she is still doing Betaseron every other day.
Any suggestions would be appreciated....thanks

Does she always take the minocycline with food? I'm okay with minocycline unless I don't eat food and then I usually feel very unwell.

Your daughter should stop both Minocycline and aspirin for several days, perhaps a week, and take OTC Prilosec (omeprazole) 40 mg daily. When she fully recovers she can start Minocycline again with lots of food. Dairy products should be excluded within two hours before and after Minocycline.They impair absorption. No more aspirin.