Re: What if not bacteria but virus?????
Posted: Sun Jun 16, 2013 10:23 am
option 1) see how far they get you
option 2) ignore the research
straight google results http://scholar.google.ca/scholar?q=sele ... as_sdt=0,5
Selenium nucleophiles for the preparation of antiviral nucleosides
NDP Cosford, RF Schinazi - The Journal of Organic Chemistry, 1991 - ACS Publications
The reactivity of nucleophilic selenium species toward nucleoside derivatives has been examined. A number of new 2'-deoxyribose nucleosides have been synthesized using this methodology. The cis elimination of the selenoxide obtained from the oxidation of the ...
Selenium as an antiviral agent
MA Beck - Selenium, 2001 - Springer
Abstract Recent work with selenium has demonstrated that a deficiency in this trace mineral will lead to increased viral pathogenesis. Selenium-deficient animals infected with a viral pathogen demonstrate immune dysfunction, including altered chemokine and cytokine ...
Azaanalogues of ebselen as antimicrobial and antiviral agents: synthesis and properties
H Wójtowicz, K Kloc, I Maliszewska, J Młochowski… - Il Farmaco, 2004 - Elsevier
... The different analogues of ebselen—unsubstituted benzisoselenazol-3(2H)-one (2a) 2-pyridylbenzisoselenazol-3(2H)-ones (2b–h) and 7-azabenzisoselenazol-3(2H)-ones (3a–j) were designed as new selenium-containing antiviral and antimicrobial agents and synthesized. ...
Serum selenium concentrations in rheumatoid arthritis.
JR O'Dell, S Lemley-Gillespie, WR Palmer… - Annals of the …, 1991 - ard.bmj.com
... oxidative damage. Selenium has been shown to have anti- proliferative, anti-inflammatory, antiviral, and immune altering effects. Serum selenium ... Antiviral effects of selenium have also been postulated. In vivo animal studies ...
Selenium in the maintenance and therapy of HIV-infected patients
GN Schrauzer, J Sacher - Chemico-Biological Interactions, 1994 - Elsevier
... encouraged. 2. Antiviral effects of selenium Chronic suboptimal selenium intakes result in a weakening of the immune response, as was recently demonstrated in chronic
gut failure patients maintained on home TPN. The patients ...
Antifungal, antibacterial, antiviral and cytotoxic activity of novel thio-and seleno-azoles
D DEIDDA, G LAMPIS, C MAULLU, R POMPEI… - Pharmacological …, 1997 - Elsevier
A series of pentaatomic heterocyclic compounds containing sulphur or selenium in position 2, were tested for cytotoxicity, antiviral and antimicrobial activitie. ...
Do unsaturated fatty acids function as endogenous antibacterial and antiviral molecules?
UN Das - The American journal of clinical nutrition, 2006 - Am Soc Nutrition
... Washington, DC: National Academy Press, 2000. 8. Xia Y. Dietary selenium reference intake.
In: Chinese DRIs. Beijing, China: Chinese Nutrition Society, 2000:210–25 (in Chinese). Do unsaturated fatty acids function as endogenous antibacterial and antiviral molecules? ...
Synthesis and antiviral activity of 3-cyano-2 (1H) pyridine selenones
VY Mortikov, VP Litvinov, AM Shestopalov… - Pharmaceutical …, 1991 - Springer
... UDC 615,281:547.82 Selenium organic compounds are known to exhibit a high degree of antiviral activity [7, i0, 12]. ... Thus, in analyzing the results of the experimental data on the screening of selenium- containing compounds, one can see that they manifest antiviral activity. ...
High risk of HIV-related mortality is associated with selenium deficiency
MK Baum, G Shor-Posner, S Lai, G Zhang… - JAIDS Journal of …, 1997 - journals.lww.com
... It was highest (19.9) for selenium deficiency over time (p< 0.0001). Neither vitamin B 6 nor vitamin E deficiency was associated with an increased risk for mortality. The use of zidovudine and other antiviral regimens was not significantly associated with mortality. ...
Selenium-based pharmacological agents: an update
SW May - Expert opinion on investigational drugs, 2002 - informahealthcare.com
... A 1999 review by this author in Expert Opinion on Investigational Drugs [21] focused on the development of selenium-based antihypertensive, anticancer, antiviral, immu- nosuppressive and antimicrobial agents, as well as on orga- noselenium compounds which reduce ...
option 2) ignore the research
straight google results http://scholar.google.ca/scholar?q=sele ... as_sdt=0,5
Selenium nucleophiles for the preparation of antiviral nucleosides
NDP Cosford, RF Schinazi - The Journal of Organic Chemistry, 1991 - ACS Publications
The reactivity of nucleophilic selenium species toward nucleoside derivatives has been examined. A number of new 2'-deoxyribose nucleosides have been synthesized using this methodology. The cis elimination of the selenoxide obtained from the oxidation of the ...
Selenium as an antiviral agent
MA Beck - Selenium, 2001 - Springer
Abstract Recent work with selenium has demonstrated that a deficiency in this trace mineral will lead to increased viral pathogenesis. Selenium-deficient animals infected with a viral pathogen demonstrate immune dysfunction, including altered chemokine and cytokine ...
Azaanalogues of ebselen as antimicrobial and antiviral agents: synthesis and properties
H Wójtowicz, K Kloc, I Maliszewska, J Młochowski… - Il Farmaco, 2004 - Elsevier
... The different analogues of ebselen—unsubstituted benzisoselenazol-3(2H)-one (2a) 2-pyridylbenzisoselenazol-3(2H)-ones (2b–h) and 7-azabenzisoselenazol-3(2H)-ones (3a–j) were designed as new selenium-containing antiviral and antimicrobial agents and synthesized. ...
Serum selenium concentrations in rheumatoid arthritis.
JR O'Dell, S Lemley-Gillespie, WR Palmer… - Annals of the …, 1991 - ard.bmj.com
... oxidative damage. Selenium has been shown to have anti- proliferative, anti-inflammatory, antiviral, and immune altering effects. Serum selenium ... Antiviral effects of selenium have also been postulated. In vivo animal studies ...
Selenium in the maintenance and therapy of HIV-infected patients
GN Schrauzer, J Sacher - Chemico-Biological Interactions, 1994 - Elsevier
... encouraged. 2. Antiviral effects of selenium Chronic suboptimal selenium intakes result in a weakening of the immune response, as was recently demonstrated in chronic
gut failure patients maintained on home TPN. The patients ...
Antifungal, antibacterial, antiviral and cytotoxic activity of novel thio-and seleno-azoles
D DEIDDA, G LAMPIS, C MAULLU, R POMPEI… - Pharmacological …, 1997 - Elsevier
A series of pentaatomic heterocyclic compounds containing sulphur or selenium in position 2, were tested for cytotoxicity, antiviral and antimicrobial activitie. ...
Do unsaturated fatty acids function as endogenous antibacterial and antiviral molecules?
UN Das - The American journal of clinical nutrition, 2006 - Am Soc Nutrition
... Washington, DC: National Academy Press, 2000. 8. Xia Y. Dietary selenium reference intake.
In: Chinese DRIs. Beijing, China: Chinese Nutrition Society, 2000:210–25 (in Chinese). Do unsaturated fatty acids function as endogenous antibacterial and antiviral molecules? ...
Synthesis and antiviral activity of 3-cyano-2 (1H) pyridine selenones
VY Mortikov, VP Litvinov, AM Shestopalov… - Pharmaceutical …, 1991 - Springer
... UDC 615,281:547.82 Selenium organic compounds are known to exhibit a high degree of antiviral activity [7, i0, 12]. ... Thus, in analyzing the results of the experimental data on the screening of selenium- containing compounds, one can see that they manifest antiviral activity. ...
High risk of HIV-related mortality is associated with selenium deficiency
MK Baum, G Shor-Posner, S Lai, G Zhang… - JAIDS Journal of …, 1997 - journals.lww.com
... It was highest (19.9) for selenium deficiency over time (p< 0.0001). Neither vitamin B 6 nor vitamin E deficiency was associated with an increased risk for mortality. The use of zidovudine and other antiviral regimens was not significantly associated with mortality. ...
Selenium-based pharmacological agents: an update
SW May - Expert opinion on investigational drugs, 2002 - informahealthcare.com
... A 1999 review by this author in Expert Opinion on Investigational Drugs [21] focused on the development of selenium-based antihypertensive, anticancer, antiviral, immu- nosuppressive and antimicrobial agents, as well as on orga- noselenium compounds which reduce ...