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Long-term(?) Antibiotic Treatment with Roxithromycin in Patients with Multiple Sclerosis

R. Woesner et al, Dept. of Neurology, Westpfalz Medical Center, 67655 Kaiserslautern, Germany

http://www.springerlink.com/content/d8lk7402338677x1/

They found no difference in the EDSS of relapsing remitting people after treatment of a year, compared to people on a placebo, however, the long term treatment consisted of three periods of six weeks over the course of a year, and only one antibiotic was involved. Is this surprising? What is the use of a trial unless it is done properly, and what other treatment for MS is used in this half-baked way?

Sarah

Another short-tempered artist here. My surprise at learning that longterm antibiotics is ineffective is astronomical since I am PPMS and have done for 27 months a 3 antibiotic protocol devised by those who should know - Drs. Stratton and Wheldon. Since I am not dead, they must have worked. Not only am I not dead, I went up on the barn roof yesterday, after positioning the ladder, and put tar on the new rust holes. Something I still can't do is levitate, hence the need for the ladder, a 20' aluminum extension that I single-woman-handled to its position 50' away from its storage. The protocol, like any of the arts, is not for the faint of heart.

Rica

Now that made me laugh! Everyone's going to be wondering where the short tempered artist bit came from! So who's going to tell them? Gosh, did you really do all that? I did try to levitate, or at least run, just before Xmas, but I just ended up in a heap on the pavement, envelopes scattered all around. Actually, I was thinking of changing short tempered to impatient, but won't now.

Well, a year consists of 52 weeks, so eighteen weeks split into three means very little, does it? Admittedly I had only ever taken two five day courses of whatever abx before, but not to treat such a difficult chronic infection. Yet one more time it seems to come down to people being too limited by their specialisation: this trial was led by a neurologist. My neurologist has tried to prove a point recently by doing a few six week courses of doxycycline. Neither use nor ornament.

Sarah