This Is MS Multiple Sclerosis Knowledge & Support Community

Dear Sarah,

Could not Cpn be implicated also in PPMS? I understand that the antibiotic regimen seems to work best for RRMS and maybe SPMS, but it may still work also on PPMS by stopping progression. Or does the science say otherwise?

Regards,
Phil

The received wisdom is that CPn probably is not implicated in PPMS, which alone of all the types of MS does seem to be a different type of disease. But this does not mean that the immunomodulatory qualities of certain of the antibiotics will not work, if nothing else. If someone with PPMS tried this and seemed to stop or at least slow down the progression, this surely would be no bad thing.

Sarah

Sarah,

I am certainly interested in your therapy as well as a few others I have read about here. You may have already answered my questions before , but after reading so many posts it's hard to remember them all and much easier to ask a direct question. I understand that the antibiotics are working for you , and I would never want to be seen as questioning the judgement of you or your husband. My question is this. Does your husband believe that it is the anti-microbial properties of the antibiotics that are helpful or does he believe that it is actually some kind of neuro-protective effect of the drug/s ?
If it is believed to be primarily a neuro-protective process then maybe it's possible that some of the other substances with similar properties might work as well without the risk of lupus-syndrome? Things like the omega-3 EFA's or vitamin D or whatever?
If my condition gets much worse I'll be willing to try almost anything but would prefer to start with something with the least potential for ill effects.

Again you have probably addressed this next point as well , but as others say, I feel like my brain is all foggy right now. Does this REALLY appear to be a promising avenue of treatment for a significant number of people? Are your husband and the other docs duplicating your results in their other patients?

Tracy

Tracy,

David is a microbiologist who is treating MS as an infective disease, largely of CPn. To both of us the neuro-protective properties of some of the drugs are a sideline. One could not have expected the great improvement in the two subsequent MRIs from just neuropotection. Basically, on starting thetreatment, the disease was stopped in its tracks. I have had no exacerbations since and none of the existing lesions are active. Neither have I had any new lesions.

To my mind, a bit foggy at this time of night (23.53) and after a hard days painting and two glasses of wine, it is a very promising treatment for more than a significant number of people. Both David and other Docs are duplicating my results. It started with the peole at Vanderbilt University in Nashville, when Charles Stratton, another microbiologist alerted one of the neurologists, Ram Sriram, to the similarity with the MRI scans of MS patients to some people with neuro-lyme disease and other infective, cell wall deficient brain diseases. This dates back to the nineteenth century, when the French physician, Charcot, amongst others, was of the mind that MS was an infective disease. The trouble was that nobody could isolate the infection. CPn was only discovered to be a pathogen less than 20 years ago. Sriram at the moment is one of the few neurologists to be able to change their way of thinking. That's all I can say really, apart from the fact that I, amongst others, are being able to turn our backs on MS.

Sarah

Sarah,

I just realized that I had neglected to thank you for your last reply. I really do appreciate your taking time to answer my questions. I would probably have no problem making the trip to California or wherever required, but am still weighing options at this point. Of course we have only so many options to begin with. I guess you have probably posted most of your info already. If you have anything else that might help completely convince me I'd be willing to listen- but was there something about having to wait until your husband has a chance to publish his findings? Anyway , I didn't want you to think that I was ungrateful for your willingness to share.
Tracy

Tracy,

Thank you but don't worry, I hadn't even noticed because I was just too busy, setting up a new printer, reorganising my studio to fit in in and so on. I don't think I have anything new particularly to say at the moment, but as soon as any new papers are published by the people at Vanderbilt, my husband or whoever, I will post them in Links on chlamydia pneumoniae", a thread started by Daunted somewhere in the this section:

http://thisisms.com/modules.php?name=Fo ... opic&t=915

Have you read everything here?

Sarah

Hi Sarah,

Would it be possible to get an email so i am able to contact either yourself or your husband in regards to treating ms with the antibiotics, I have got my neurologist to start my treatment so far it's only been 6 weeks, i live in Australia & my specialist didn't even know anything about it, i took all the info into him and he was broadminded enough to let me try it, he is a wonderful neurologist his name is Dr Serisier & he has been treating me for 18 years and I am only 35 years old. I am having some issues which i would like to discuss please.

Mandy

Hello Mandy,

My email can be found here: http://www.avenues-of-sight.com I will ask David later if I can give you his, but you might be better asking me what you want to know in the first instance because he is very busy with new patients this week.

Don't forget that we are twelve hours behind you!

Sarah

HI Sarah,

Would Dr. Powell be able to help a Canadian? Or do you know any Canadian doctors who are treating CPn using your husband's protocol?

Thanks so much!