Posted: Fri Jul 30, 2010 5:20 pm
jimmy...the "absence of zinc" just means they knew it was iron deposited-- not zinc. (SWI can detect different mineralization in the brain, including copper or zinc, and the XRF technology allowed them to differentiate the minerals they saw on MRI) All that sentence means is they knew it wasn't zinc they saw. This study has nothing to do with a lack of zinc in serum levels....although I know there are many studies regarding the need for zinc...
I thought I was clear above...will try again. Iron found in the brain is not about the levels of metals in the blood. Cellular death can cause iron deposition. It's not necessarily about serum levels. Back to Haacke. Iron seen on SWI can be from:
cheer
I thought I was clear above...will try again. Iron found in the brain is not about the levels of metals in the blood. Cellular death can cause iron deposition. It's not necessarily about serum levels. Back to Haacke. Iron seen on SWI can be from:
Iron in the brain is not about iron overload or a lack of minerals in serum. It's a sign of cellular death, microbleeds, reflux or the genetic instability of ferritin.1.oligodendrocyte ferritin after macrophage activity (dead cells leave an iron trail)
2.iron from blood products (actual microbleeds into brain tissue)
3. iron in the vessel wall or some combination of these.
The iron that is measured here may represent hemosiderin which comes from the breakdown of blood not from other sources of iron. There is no evidence at this time that there are stray sources of iron causing this problem, not has that been proposed in this research.
cheer