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lyme disease produces vascular changes

Posted: Fri Jul 30, 2010 12:13 pm
by frodo
Looking for differences between brain lesions in Lyme (LNB) and MS I have found an article that states that Lyme disease produces vascular damage. I quote:

"There is increasing evidence that inflammatory changes in CNS blood vessels, such as diffuse or focal vasculitis or cerebrovascular injury, may be an important factor in the development of the CNS lesions and dysfunction in LNB"

and

"It is conceivable that Lyme borreliosis may also cause vascular damage in the CNS, because it is known to cause vasculitis and perivascular inflammation in several other
of CNS blood vessels and then adhere to the glial cells organs outside the CNS"

Maybe another clue?

Edit: I forgot the link. Here it is.
http://brain.oxfordjournals.org/cgi/rep ... 6/2143.pdf

Edit 2: By now, I have been unable to find a report explaining differences between MS and Lyme brain lesions. In fact, I have found some people saying that they look the same even under autopsy.

Posted: Fri Jul 30, 2010 8:24 pm
by sbr487
If the type of vascular issues are similar to what we see in MS then it should clearly mimic MS issues like lesions etc.

Posted: Fri Jul 30, 2010 8:46 pm
by elyse_peace
thanks, frodo -
i appreciate the link.
i have lyme and ms, so i guess my veins are under siege.

Posted: Fri Jul 30, 2010 9:53 pm
by aliyalex
my MS/Lyme doc old me that the infections live in the lymph system, which is dense. they jump to the vascular system b/c of the rich blood. he had me on antimicrobials for 10 months and the dieoff came out of my face and above the armpits, heavy lymph areas.

my right jugular vein area has been constantly itching. for years. i'll have diagnosis and hopefully treatment at the end of August. we'll see. it is truly a time of discovery.

Posted: Sat Jul 31, 2010 3:18 pm
by NotFound
Oh great. What do I have then?

According to my neurologist I have MS.

According to Dr, Kostecki I have Lyme.

According to both of the Dopplers, one MRV, one CT scan and one catheter venography my veins ARE JUST FINE. :roll:

Posted: Sat Jul 31, 2010 3:30 pm
by aliyalex
notfound, interesting name.

sounds like you have some avenues to explore. lymenet.com has a lot of success stories of healing MS presentation. i dont think antibiotics are a good treatment . if you want more specific info PM me.

Posted: Thu Aug 05, 2010 3:55 am
by Whitey
NotFound: My brother got tested for Lyme while we were in Tychy (Dr. Kostecki) at the end of June, and it came back positive. You must be carrefull because there are a lot of false positives and false negatives with Lyme. If you want to be sure, get tested again at home with the Western Blot test. My brother has just started his treatment based on the test from Poland.

Posted: Thu Aug 05, 2010 6:36 am
by aliyalex
Whitey,

i've been in lyme treatment for years and I have heard of false negatives, in fact I had one, but not false positives. In the latter case, I believe it is just a case of chronic borreliosis that is very hard to treat.

When I found my lyme doc, he was one who got the most difficult cases and I travelled to Seattle to see him for 2 years+.

Posted: Thu Aug 05, 2010 3:30 pm
by NotFound
aliyalex wrote: if you want more specific info PM me.
Alex, just wondering if you got my PM. I PMed you a while ago.

Posted: Thu Aug 05, 2010 3:37 pm
by aliyalex
notfound - no! i never got it. i just checked to see if i missed it. i didn't. would you resend?

Posted: Thu Aug 05, 2010 7:30 pm
by elyse_peace
According to the doc who diagnosed my lyme, 5% of Lyme patients are seronegative. I had gotten repeated negative results from Quest tests. Thus the testing at Igenex, a lab that tests only for tick-borne diseases. That includes the various co-infections to Lyme: Erlichiosis, Babesia, Bartonella, etc. The co-infections are not viral, but parasitic.
I later saw a Lyme specialist to ask his opinion of my Lyme doc's diagnosis. His opinion was that I have both Lyme and MS.
The difficult thing with Lyme is that a spirochete can consume a cell, and use the cell membrane as a way of concealing itself. Stealth bombers, if you will.
Nasty, any way one looks at it.