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But then i wonder about mononucleosis how this could relate CCSVI.
Wife was diagnosed with mono at age 16. At age 42 diagnosed with MS.
This link shows a possible correlation with MS and mono.

http://www.health.am/ab/more/mononucleo ... sclerosis/


Then i find it interesting that TMrox came down with Transverse Myelitis.
She feels it could have been a virus while on a trip to Africa (read 2nd paragraph under title "Diagnosed with Transverse Myelitis, now what?").

URL

So question is could a virus cause CCSVI..?

But then there again wife has a cousin that was diagnosed with MS.
Unknown if she had Mono.

Could it be possible that a person could have genetic CCSVI at birth, then later on in life come down with mono leading to diagnosis of MS later on in life..?

Or that mono makes it easier for areas with malformations to have inflammation?

I seem to remember a Zivadinov effort that concluded there are mostly antibodies to dormant mono, not to a current or re-infection. How those antibodies interacted with 'MS', I do not remember.

1eye wrote:Or that mono makes it easier for areas with malformations to have inflammation?

I seem to remember a Zivadinov effort that concluded there are mostly antibodies to dormant mono, not to a current or re-infection. How those antibodies interacted with 'MS', I do not remember.

I may have this backwards but I believe mono is a byproduct of the Epstein Barr Virus. As well the Virus can stay in the system with the Mono turning on or off...Either way I had it around 16 yrs as well and Ms at 40. Here we go with the chicken and the egg thing. If Zamboni turns out to be correct with the theory of CCSVI in vetro and malformations at birth, unfortunately it doesnt explain the effect of Epstein Barr...

elliberato wrote:

1eye wrote:Or that mono makes it easier for areas with malformations to have inflammation?

I seem to remember a Zivadinov effort that concluded there are mostly antibodies to dormant mono, not to a current or re-infection. How those antibodies interacted with 'MS', I do not remember.

I may have this backwards but I believe mono is a byproduct of the Epstein Barr Virus. As well the Virus can stay in the system with the Mono turning on or off...Either way I had it around 16 yrs as well and Ms at 40. Here we go with the chicken and the egg thing. If Zamboni turns out to be correct with the theory of CCSVI in vetro and malformations at birth, unfortunately it doesnt explain the effect of Epstein Barr...

Yes it does. It also may explain why high dose cyclophosphamide and rituximab work with MS. They both destroys B cells where the dormant EBV hides. No B cells, no EBV. I have never read anything about people with whom HDC failed and whether or not they get reinfected. I'd be very interested to find out.

It does say that all people with these particular congenital malformations are going to get 'MS', even though some say they don't necessarily. My old favorite, tricuspid insufficiency (have I been calling it 'bicuspid'? Oh dear...) is very often asymptomatic. So may be CCSVI, sometimes. If it is, the people who have it might still get MS, down the line. But there's no reason I can think of why CCSVI, or other conditions caused by CVMs couldn't be more susceptible to mono. The throat is suspiciously nearby in both cases. Maybe mono is short-term, and 'MS' is longer-term damage, and both are consequences of VMs. Similar arguments for thyroid.