This Is MS Multiple Sclerosis Knowledge & Support Community

Folks,

I contacted Dr. Steinman today to understand his views on CCSVI. Needless to say, the good Dr is pretty much aware of CCSVI.

Here is his response to my first e-mail:

Dear X__X,
I think CCSVI is interesting. I applied with colleagues at Stanford for two grants to study CCSVI. We had proposed to do state of the art imaging on veins in the neck in MS, as well as to try to establish an animal model. Unfortunately our grants were not funded.
Only by doing good research in this area, will we be able to learn whether the theory is correct.
With my best regards,
Prof. Larry Steinman

I replied back thanking him and further asking him about his views patient channels through which Dr. Dake, Dr. Zivadinov are getting funding.
Here is the response to my second e-mail:

Dear X__X,

I applied for two research grants with my colleague Prof. Mike Dake here at Stanford, and unfortunately neither grant was funded.
If patient funding channels want to provide money for research on CCSVI, I would have no objections. I see from reading various blogs that Dr. Dake is getting funding from such groups like the MSketeers already.

I have no objections to having my response at thisisms.com

I read the forum regularly.

Best,
Prof. Larry Steinman

I really wish someone like him could carry out research to test validity of CCSVI. Hope we can do something about it ...

I wonder if Dr. Steinman has had any luck going forward with his lisinopril investigations?

Yea I know this is a drug but the idea that blood pressure medication could have a positive affect on cerebral perfusion seems a definite CCSVI parallel to me. One that could potentially prove useful someday to those who are not able to benefit from angioplasty.

"The right to search for truth implies also a duty; One must not conceal any part of what one has recognized to be true" A. Einstein

i believe Dr S is being less than forthcoming. Just a hunch.

Being in the position that he is, I don't think one can make statements so easily. Remember he is the person who warned that tsyabri like medicine can harm. How of many of them do you find these days ...

He must be the doctor at Stanford who was said to be working on an animal model. But it must've been a proposal to do such work, and with the proposal turned down, no animal model is being developed at Stanford? That is disappointing if it is the case.

There are animal models being looked at @ Stanford. Also. there are two possible spontaneous animal models that have been found by a veterinary neurologist interested in CCSVI, Filippo Adamo. there are 91 race horses in Quebec who have bilateral jugular blockages and acquired exercise intolerance. and sa family group of border collies in saskatchewan with unexplained exercise induced collapse. DrAdamo is hoping to scan these animals looking for MS plaques in the brains and venous insufficiency in the dogs. (it is already proven in the horses)

It is my understanding from what i was told by the neurology department at stanford, that Dr S is not working on CCSVI in MS and from his early hostile statements he seems to be among those who are actively working to prevent this work. I would be delighted to learn that this is a false rumor. When he and his fellow immunology based researchers join with the IRs and study CCSVI in MS together, as the dean suggested, we will really get the answers we need.

msscooter wrote:There are animal models being looked at @ Stanford. Also. there are two possible spontaneous animal models that have been found by a veterinary neurologist interested in CCSVI, Filippo Adamo. there are 91 race horses in Quebec who have bilateral jugular blockages and acquired exercise intolerance. and sa family group of border collies in saskatchewan with unexplained exercise induced collapse. DrAdamo is hoping to scan these animals looking for MS plaques in the brains and venous insufficiency in the dogs. (it is already proven in the horses)

It is my understanding from what i was told by the neurology department at stanford, that Dr S is not working on CCSVI in MS and from his early hostile statements he seems to be among those who are actively working to prevent this work. I would be delighted to learn that this is a false rumor. When he and his fellow immunology based researchers join with the IRs and study CCSVI in MS together, as the dean suggested, we will really get the answers we need.

Dr. S made hostile statements. Can you point me to one?
On the contrary, he planned to collaborate with Dr. Dake.
He did not get grant for CCSVI study. I would expect anti CCSVI people to be flush with money. BTW, his own statement is above...

Steinman: "Dake needs more strenuous oversight" he is part of the team reaching across disciplines, in contravention to the principles of academic freedom, trying to provide that "strict oversight." All his work is with the now debatable EAE model of MS, he has an apparent conflict of interest.



http://online.wsj.com/article/NA_WSJ_PU ... 35240.html