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gotcha!

I am concerned that some people are reading too much into this piece of research.
It is not a question of MRVs being good or bad, rather what we can learn from them. Standard MRV is of limited use because it does not give information on flow (see Cheer's post). The cost of before and after MRVs may be an issue for some people (they are not cheap), plus you need an expert to interpret the data (see Normb's post).
I still am trying to discover if Dr Haacke's MRV will detect scepta and webs in the trunk. Anyone know for sure, with evidence ?
If Dr Haacke's MRV can give a diagnosis of stenoses (all types) in all major veins in the neck and trunk it is a major step forward as MRV is non invasive. (Selective Venography is invasive and Doppler only scans neck veins).

I repost - for me the key recommendation from Mark Haacke is:

A consensus or white paper on how to do the PTA should be prepared.

This should mean that pwMS receive the best therapy.

MarkW

PS This is all about flow cos flow of blood and CSF moves oxygen into and waste products out of the CNS. Differences from 'normal' may not be significant for pwMS as reduced flow could be the straw that broke the camels back and gave us MS.

MarkW wrote:I still am trying to discover if Dr Haacke's MRV will detect scepta and webs in the trunk. Anyone know for sure, with evidence ?

In the presentation link there was a page with an MRV image done of the azygous but it was blurry, not controlled for motion. There is something about needing cardiac shielding too to image the azygous. Not sure if that was from this presentation or elsewhere. I'll double-check and get back....

between Haake and the guy from Harvard who studies iron the level of discourse has noticeably risen around here.

that is I only understand every fourth word rather than every second.

Here's what was said about the azygous:

Example of azygous vein imaging not yet motion corrected. Potential is there to do better.
In this case, the azygous looks reasonably uniform.
Data can be viewed in 3D and flow is also acquired for these vessels.

If they can show flow in the azygous, that should be enough to indirectly show if there are webs there.

cheerleader wrote:

marcstck wrote:Cheer-has Haacke studied any healthy controls? We really need a control group to compare these findings to. On their own, they appear quite impressive, but what we really need to know is their deviation from whatever is the "norm".

Dr Haacke is currently testing normals, Marc. He was the first, and is happy to report he has great blood flow. He's now testing students.
cheer

Here is what Dr. Haacke said about this in the linked presentation:

We need to image as many normals as possible. Currently the number of patients being imaged and/or treated is in the 1000s, and we need age matched normals to go with this patient population.