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James Watson's discovery of DNA structure in 1953

Posted: Fri Oct 07, 2011 2:17 pm
by 1eye
In unix-land this technique would be called a "diff". It finds deletions from other DNA (like the parent's, in autism) by comparing one to another genome. In this TED talk, Watson talks about the discovery of DNA's structure, but when he goes on to talk about diseases it gets really interesting. They use a specialized chip to do the scanning. If we could do this for "MS" it would probably be very revealing.

Re: James Watson's discovery of DNA structure in 1953

Posted: Fri Oct 07, 2011 11:58 pm
by sbr487
1eye,

** I am not an expert but here is my take **

I have read some paper relating to genes and MS. Most of the current research assume the culprit is a malfunctioning immune system and then try to find the culprit genes (within the known genes that control the immune system). If CCSVI is true then you won't find anything wrong in the immune system, since nothing is inherently wrong there. So, as long as the starting point is incorrect, the issue likely to escape (remember starting point & local minimas, 1eye)

The second part of the problem is that difference between genes may or may NOT mean anything. For example, it is normal for genes to undergo mutation. Part of normal process. But every mutated gene need not cause a specific issue.

But yes, the current issue in doing exhaustive gene scanning is probably time. And if technology improves (like chips doing this task) then complete scanning might become routine ...

Some exciting times ahead ...

Re: James Watson's discovery of DNA structure in 1953

Posted: Sat Oct 08, 2011 6:14 pm
by 1eye
it seems that cases where complete deletion is present are scannable with this chip...