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tmb associated with jugular reflux

Posted: Fri Jan 06, 2012 6:18 pm
by Cece
http://onlinelibrary.wiley.com/doi/10.1 ... 21299/full
Abstract
Objective
Transient monocular blindness (TMB) attacks may occur during straining activities that impede cerebral venous return. Disturbance of cerebral and orbital venous circulation may be involved in TMB.

Methods
Duplex ultrasonography and Doppler-flow measurement of jugular and retrobulbar veins were performed in 134 consecutive patients with TMB and 134 age- and sex-matched control subjects. All recruited patients received thorough examinations to screen for possible underlying causes.

Results
Of the 134 patients with TMB, 48 patients had ipsilateral carotid arterial lesion and 7 patients had TMB attack(s) caused by cardiac embolism. Of the remaining 79 patients with undetermined cause, 46 had 3 or more TMB attacks (undetermined-frequent group) and 33 had fewer than 3 attacks. In comparison with the control subjects, the TMB patients had greater frequencies of jugular venous reflux (57 vs 30%; p < 0.0001; odds ratio [OR]: 3.079, 95% confidence intervals [CI]: 1.861–5.096) and flow reversal in the superior ophthalmic vein (RSOV; 37 vs 9%; p < 0.0001; OR: 6.052, CI: 3.040–12.048). The undetermined-frequent group had the greatest frequencies of jugular venous reflux (74%, 34 patients; OR: 6.66, CI: 3.13–14.17) and RSOV (59%, 27 patients; OR: 6.51, CI: 3.12–13.58). Of the 50 patients with RSOV, 47 (94%) had RSOV on the side of the TMB attacks.

Interpretation
The increased incidences of jugular and orbital venous reflux in TMB patients suggest that disturbance of cerebral and orbital venous circulation is involved in the pathogenesis of TMB, especially among patients with frequent attacks of undetermined cause. Ann Neurol 2008
Cheer has probably already posted this sometime in the past. I don't remember reading it before. Jugular and orbital venous reflux is bad for our eyes.

Re: tmb associated with jugular reflux

Posted: Sat Jan 07, 2012 2:19 am
by CureOrBust
Shayk - http://www.thisisms.com/forum/chronic-c ... ml#p116055 link lower in the post
gibbledygook - http://www.thisisms.com/forum/chronic-c ... ml#p127018 this one has two referenced articlees by the same team.
ikulo - http://www.thisisms.com/forum/chronic-c ... 16558.html

The third one starts from a referring article. but no cheerleader. :smile:

I found these using Google

Re: tmb associated with jugular reflux

Posted: Sat Jan 07, 2012 7:25 am
by Cece
:) I was running out of time last night or I would have done that google search. I actually left my computer open with about ten interesting articles pulled up...and my husband with good intentions shut the computer down, losing all of them.

Credit to Shayk, gibbledygook and ikulo for finding this earlier. I see it as more reason to think that some of the eye issues seen in MS, such as optic neuritis and pars planitis, could be related to jugular reflux.