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CCSVI congenital?!?

Posted: Fri Feb 24, 2012 10:01 am
by Nasti
Dr. Craig: optic neuritis happens early in MS until collaterals form and disease moves down to pituitary.

This statement kind of presupposes that the on start of MS is caused by a CCSVI event, which was not there before?!?

Re: CCSVI congenital?!?

Posted: Fri Feb 24, 2012 2:51 pm
by Cece
It's a mystery why optic neuritis is a disease that is less present as MS itself gets worse. He is proposing it's due to the development of collaterals, but don't collaterals develop fairly quickly?

Yes, he is linking optic neuritis to venous drainage, by saying that collaterals forming would relieve optic neuritis. No proof, however.

Re: CCSVI congenital?!?

Posted: Fri Feb 24, 2012 3:03 pm
by msscooter
There was data offered at ISNVD that in unilateral (one sided) optic neuritis the patient was invariably found to have unilateral jugular stenosis-on the same side. (mostly left)

That speaks to the association but not which came first.

Re: CCSVI congenital?!?

Posted: Fri Feb 24, 2012 3:10 pm
by msscooter
There was data offered at ISNVD that in unilateral (one sided) optic neuritis the patient was invariably found to have unilateral jugular stenosis-on the same side. (mostly left)

astounding data!

Also if there is a problem up north, like in the transverse sinus which could be congenital or acquired, it might diminish the flow to that jugular enough that the vein never develops fully, or if acquired, declines and becomes sticky and closes up. Veins need flow to stay open.

Dental infections can drain into the jugular vein and make a mess of it too.

CCSVI is both congenital and acquired.