http://discovermagazine.com/2011/jan-feb/05
Posted: Wed May 02, 2012 5:54 am
Not totally relevant to CCSVI but certain portions are probably applicable.
Most of them look at genes that regulate immune system with the basic assumption that immune system is causing the problem.
Similar could be the case with MS also where we are looking at the wrong place for a clue ...
Quite a few gene study on MS, lot of them would conclude that they did not find anything specific to suggest that faulty genes.Earlier efforts to hunt down disease-causing genes—so-called genomewide association studies—frequently came up empty-handed because medical researchers had to take cost-saving shortcuts. Instead of trolling an individual’s entire genome, they limited their search to dna regions where variations are most often seen across large populations. “It was assumed that common variants might be responsible for common diseases, but many diseases turn out to have many different rare variants at their root,” says James Lupski, a medical geneticist at Baylor College of Medicine in Houston. “That’s why the power of whole-genome sequencing blows us away. It’s the only way we can get at these rare variants.”
Most of them look at genes that regulate immune system with the basic assumption that immune system is causing the problem.
Similar could be the case with MS also where we are looking at the wrong place for a clue ...