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Somebody who seems to know me sent an email with the following titles...

articles from Techniques in Vascular and Interventional Radiology

Reported Outcomes After the Endovascular Treatment of Chronic Cerebrospinal Venous Insufficiency

The Use of Doppler Ultrasound in the Diagnosis of Chronic Cerebrospinal Venous Insufficiency

Internet-Based Social Networking and Its Role in the Evolution of Chronic Cerebrospinal Venous Insufficiency

Catheter Venography and Endovascular Treatment of Chronic Cerebrospinal Venous Insufficiency

Chronic Cerebrospinal Venous Insufficiency and Multiple Sclerosis: History and Background

Reported Outcomes After the Endovascular Treatment of Chronic Cerebrospinal Venous Insufficiency

Christopher O. Hampson, MDemail address
,
Gregory M. Soares, MD
,
Abdel Aziz Jaffan, MD

Department of Diagnostic Imaging, Warren Alpert School of Medicine at Brown University, Rhode Island Hospital, Providence, RI

Abstract
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Chronic cerebrospinal venous insufficiency (CCSVI) has recently been implicated as a potential causal factor in the development of multiple sclerosis (MS). The treatment of jugular and azygous vein stenoses, characteristic of CCSVI, has been proposed as a potential component of therapy for MS. In the few short years since Dr. Paulo Zamboni published “A Prospective Open label Study of Endovascular Treatment of Chronic Cerebrospinal Venous Insufficiency”,1 there has been tremendous patient-driven demand for treatment. Concurrently, there have been numerous publications since 2009 addressing CCSVI and its association with MS. The purpose of this article is to present a brief review of CCSVI and its association with MS and to review the available literature to date with a focus on outcomes data.

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The Use of Doppler Ultrasound in the Diagnosis of Chronic Cerebrospinal Venous Insufficiency

Sandy McDonald, RVT, RPVI, MD, FRCS(C), FACSemail address
,
J. Blake Iceton, RVT, BSE

Barrie Vascular Imaging, Barrie, Ontario

Abstract
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Chronic cerebrospinal venous insufficiency (CCSVI) may be associated with multiple sclerosis, and its treatment has been shown to potentially benefit patients with this condition. Color-assisted duplex imaging is used to assess the anatomical and physiological parameters of cerebrospinal venous function and to diagnose CCSVI. Standardized examination protocols as well as the diagnostic criteria used are important elements in ensuring reproducibility of results between centers. The objective of this article is to describe the technique our laboratory has used to assess patients for the presence of CCSVI using Doppler ultrasound.

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« PreviousTechniques in Vascular & Interventional Radiology
Volume 15, Issue 2 , Pages 153-157, June 2012
Internet-Based Social Networking and Its Role in the Evolution of Chronic Cerebrospinal Venous Insufficiency

Chido Vera, MDemail address
,
Allen Herr, MD
,
Kenneth Mandato, MD
,
Meridith Englander, MD
,
Lauren Ginsburg
,
Gary P. Siskin, MD, FSIR

Abstract
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The Internet is being seen as a growing resource for health-related information for a large number of patients. It is undeniable that its widespread presence has led to the growth of awareness that chronic cerebrospinal venous insufficiency (CCSVI) as an entity that may contribute to the symptoms experienced by patients with multiple sclerosis (MS). Social networking and file-sharing Web sites have brought patients with MS together from all over the world and have facilitated the distribution of personal experiences and information derived from medical research as it relates to CCSVI. As a result, there has been an accelerated growth in the number of patients seeking treatment for this syndrome in light of the possibility that it may improve their present condition. This article will review this phenomenon, the Internet-based resources available to MS patients seeking information about CCSVI, and the responsibilities of physicians as they participate in these online discussions.

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Catheter Venography and Endovascular Treatment of Chronic Cerebrospinal Venous Insufficiency

Kenneth Mandato, MDemail address
,
Meridith Englander, MD
,
Lawrence Keating, MD
,
Jason Vachon, MD
,
Gary P. Siskin, MD, FSIR

Department of Radiology, Albany Medical Center, Albany, NY

Abstract
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Multiple sclerosis (MS) is a disorder characterized by damage to the myelin sheath insulation of nerve cells of the brain and spinal cord affecting nerve impulses which can lead to numerous physical and cognitive disabilities. The disease, which affects over 500,000 people in the United States alone, is widely believed to be an autoimmune condition potentially triggered by an antecedant event such as a viral infection, environmental factors, a genetic defect or a combination of each. Chronic cerebrospinal venous insufficiency (CCSVI) is a condition characterized by abnormal venous drainage from the central nervous system that has been theorized to have a possible role in the pathogenesis and symptomatology of MS (1). A significant amount of attention has been given to this theory as a possible explanation for the etiology of symptoms related to MS patients suffering from this disease. The work of Dr. Zamboni, et al, who reported that treating the venous stenoses causing CCSVI with angioplasty resulting in significant improvement in the symptoms and quality of life of patients with MS (2) has led to further interest in this theory and potential treatment. The article presented describes endovascular techniques employed to diagnose and treat patients with MS and CCSVI.

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« PreviousNext »Techniques in Vascular & Interventional Radiology
Volume 15, Issue 2 , Pages 94-100, June 2012
Chronic Cerebrospinal Venous Insufficiency and Multiple Sclerosis: History and Background

Michael D. Dake, MDemail address

Department of Cardiothoracic Surgery, Falk Cardiovascular Research Center, Stanford University School of Medicine, Stanford, CA

Abstract
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Multiple sclerosis (MS) is a chronic inflammatory disorder of the central nervous system (CNS) most commonly characterized by focal areas of myelin destruction, inflammation and axonal transection. The multicentric inflammation and demyelination of the brain and spinal cord are associated with variable neurologic symptoms ranging from mild dysfunction to debilitating. Typically, these symptoms are marked by episodes of clinical worsening followed by improvement. The cause of this disease remains unclear currently, but the underlying etiology is generally considered to be immunologically based. Other factors, including genetic, environmental and infectious influences have been implicated, as well. Now recent studies have proposed that extracranial venous obstruction, termed chronic cerebrospinal venous insufficiency (CCSVI) may have a role in the pathogenesis of MS or many of its associated clinical manifestations. It is postulated that venous narrowing affecting one or more of the jugular veins and/or the azygous vein in the chest may be responsible for abnormal blood flow in the veins draining the brain and spinal cord. The abnormal flow may initiate and/or sustain a local inflammatory response at the blood-brain barrier that promote pathological changes within the CNS. This review presents the history of the relationship between the vascular system and MS and explores the background of basic and clinical investigations that led to the concept of CCSVI.

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Not a doctor or scientist, but still interested. Thanks, whoever.

Here's the link to the journal which published the articles in the June 2012 issue. I think we had this on the forum already, back in May when they were first published online....right?
http://www.sciencedirect.com/science/journal/10892516

Yeah, ok. They only just got around to sending it to me, and I should have known it was old. I don't have a subscription. I suppose they just want to sell me one. Fat chance.

Just finished watching Monk on Netflix. Seems our man Jeff was in on it.