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NPH

Posted: Sun Dec 02, 2012 6:22 am
by dania
From Dr Flanagan.
The role of the autonomic nervous system is a complex topic. Suffice it to say that the autonomic nervous system is known to fail in cases of high intracranial pressure such as traumatic brain injuries and strokes. It can also fail from arterial hypertension (high blood pressure). Some researchers suspect that hypertension and autonomic failture play a role in NPH. I further suspect that NPH may cause autonomic dysfunction which I am currently discussing on my website regarding the third ventricle. I also suspect the venous blood and CSF drainage problems can cause brain edema and NPH.
normal pressure hydrocephalus


Re: NPH

Posted: Sun Dec 02, 2012 12:04 pm
by 1eye
Can you tell from yourMRIs if you have it? Won't the ventricles be enlarged?

Re: NPH

Posted: Sun Dec 02, 2012 1:38 pm
by dania
No idea.I guess Dr Flanagan would be the one to ask.

Re: NPH

Posted: Sun Dec 02, 2012 2:40 pm
by cheerleader
1eye wrote:Can you tell from yourMRIs if you have it? Won't the ventricles be enlarged?
Yes, MRI shows the enlargement of the third ventricle, 1eye. The problem is that the enlargement of the third ventricle in MS is attributed to atrophy, not cerebral spinal fluid.
This is also a diagnostic problem in Alzheimer's Disease.
http://www.ajnr.org/content/19/5/813.full.pdf


That's what Dr. Eliott Frohman was referring to when he said enlargement of the third ventricle appears similarly in NPH and MS.
http://www.thisisms.com/forum/chronic-c ... c8147.html

cheer

Re: NPH

Posted: Sun Dec 02, 2012 9:15 pm
by blossom
thank goodness a dr. looked further even after a diag. of parkinson. "don't we only dream of"

Re: NPH

Posted: Mon Dec 03, 2012 8:06 am
by cheerleader
you're right, Blossom. It's a good thing Dr. Rosa, Dr. Flanagan, Dr. Zivadinov, Dr. Zamboni, Dr. Schelling and others are carrying on with this work. Here's a bit of history on how the NPH diagnosis first came to be. It was very controversial in its time, because neurologists were not looking at the mechanical connection to neurodegeneration. And a foreign doctor discovered it, treated patients without blinded trials and published his results. Sound familiar? :)
In the 1960s, a neurosurgeon in Bogota, Columbia made the controversial claim that he could reverse neurodegeneration by surgically diverting an excess of cerebrospinal fluid (CSF) in the brains of his patients with a shunt.

Professor Salomon Hakim first published his thesis in 1964 and then published 6 case reports of "normal pressure hydrocephalus" in The New England Journal of Medicine and the Journal of the Neurological Sciences in 1965. Hakim rose to the forefront of academic medicine as he described a newfound ability to reverse symptoms of “neurodegeneration” that had long been considered irreversible.
http://journals.lww.com/neurosurgery/Ab ... re.21.aspx

It is important to understand that today, 60 years after Hakim's discovery, treating normal pressure hydrocephalus is an accepted practice, even though diagnosing NPH is an inexact science. There were never any double blinded clinical trials for this surgery. Hakim claimed he could reverse gait impairment, cognitive problems and urinary incontinence by diverting CSF flow. And the proof was in his patients' recovery. No one cries "placebo effect!" after a patient recovers mobility, cognition or bladder control once treated for NPH.
https://www.facebook.com/note.php?saved ... 0796282297

Re: NPH

Posted: Mon Dec 03, 2012 8:33 am
by 1eye
You are ten years high in your figure of 60 years. I know this because my brother was probably the direct beneficiary of this knowledge when he was born in that year. As a newborn his head very quickly became huge. A neurosurgeon implanted a shunt in his jugular when he was weeks old, saving his life. He happened to live in the same town as we did, and probably read about Dr. Hakim.

If there is a need for a sacrificial lamb for shunt surgery in "MS", you might ask me.